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¿Debo evitar methoxyethanol acetate durante el embarazo? | VeriMom

Harmonised CLP classification for 2‑methoxyethyl acetate (CAS 110‑49‑6) is Repr. 1B, H360FD (harmonised Annex VI), therefore per your calibration this is h=3. The compound is known to be metabolised to 2‑methoxyethanol (EGME), which has demonstrated reproductive toxicity in animals and occupational settings (mechanism via the glycol‑ether metabolites is established), so mechanism is scored 2. Dermal absorption is documented as measurable for glycol ether esters, so topical exposure is low but measurable (e=1). Sources: ECHA harmonised classification and EU Cosmetic Regulation Annex II (prohibited).

ECHA regulatory hazard statements

  • H360FD

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es methoxyethanol acetate seguro durante el embarazo?
Harmonised CLP classification for 2‑methoxyethyl acetate (CAS 110‑49‑6) is Repr. 1B, H360FD (harmonised Annex VI), therefore per your calibration this is h=3. The compound is known to be metabolised to 2‑methoxyethanol (EGME), which has demonstrated reproductive toxicity in animals and occupational settings (mechanism via the glycol‑ether metabolites is established), so mechanism is scored 2. Dermal absorption is documented as measurable for glycol ether esters, so topical exposure is low but measurable (e=1). Sources: ECHA harmonised classification and EU Cosmetic Regulation Annex II (prohibited).
¿Es methoxyethanol acetate seguro durante la lactancia?
Same hazard basis applies for lactation: harmonised Repr.1B (H360FD) and metabolic conversion to EGME indicate a confirmed reproductive hazard potential for mother/infant exposure (h=3). Mechanistic evidence of metabolite‑mediated toxicity supports m=2. For topical use, dermal uptake is measurable but not high (e=1); data on milk transfer are limited but given systemic absorption and classification concern, lactational exposure is plausible and caution is warranted.
¿Es methoxyethanol acetate seguro para la piel del bebé?
Hazard remains h=3 because of harmonised H360FD. Mechanistic concerns (metabolic conversion to EGME) remain (m=2). Exposure is increased for infants (per your rule +1) because infant skin has higher absorption/SA:weight and the parent compound is dermally absorbable — adult e=1 → baby e=2. The substance is explicitly prohibited in cosmetics under EU Cosmetic Regulation Annex II, so it should not be present in products for infants/children.
¿Cómo puntúa VeriMom a methoxyethanol acetate?
VeriMom puntúa methoxyethanol acetate en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a methoxyethanol acetate en el embarazo?
Consulta nuestra lista de alternativas seguras a methoxyethanol acetate según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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