¿Debo evitar methoxydiglycol durante el embarazo? | VeriMom
ECHA lists diethylene glycol monomethyl ether (methoxydiglycol, CAS 111-77-3) with a harmonised CLP classification for reproductive toxicity (H360 - may damage fertility or the unborn child), which places it in the highest hazard band for developmental/reproductive effects. Animal and mechanistic work show it is metabolised to methoxyacetic acid, a metabolite implicated in reproductive/developmental toxicity in multiple studies, supporting a demonstrated mechanism. Dermal/topical use gives measurable systemic absorption for small glycols used as solvents, so exposure from cosmetics is non‑negligible (moderate). ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es methoxydiglycol seguro durante el embarazo?
- ECHA lists diethylene glycol monomethyl ether (methoxydiglycol, CAS 111-77-3) with a harmonised CLP classification for reproductive toxicity (H360 - may damage fertility or the unborn child), which places it in the highest hazard band for developmental/reproductive effects. Animal and mechanistic work show it is metabolised to methoxyacetic acid, a metabolite implicated in reproductive/developmental toxicity in multiple studies, supporting a demonstrated mechanism. Dermal/topical use gives measurable systemic absorption for small glycols used as solvents, so exposure from cosmetics is non‑negligible (moderate). ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
- ¿Es methoxydiglycol seguro durante la lactancia?
- Because the substance has a harmonised H360 reproductive classification and is metabolised to methoxyacetic acid (a known reproductive toxicant), there is concern for transfer to nursing infants; advisory bodies note uncertainty but flag lactation as a relevant route and the absence of data on milk levels. Dermal/topical use can produce systemic levels (measurable), so breastfeeding exposure cannot be ruled out. ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
- ¿Es methoxydiglycol seguro para la piel del bebé?
- Hazard (H360) remains highest (h=3) due to harmonised CLP classification and animal evidence. Mechanistic concern (metabolism to methoxyacetic acid) is demonstrated. Exposure (e) is increased by +1 for infants (per your instruction): because the compound is a small, moderately skin‑permeable solvent with measurable dermal uptake in adults, infant skin (higher SA:weight and immature barrier) raises likely systemic exposure to high. ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
- ¿Cómo puntúa VeriMom a methoxydiglycol?
- VeriMom puntúa methoxydiglycol en 13/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a methoxydiglycol en el embarazo?
- Consulta nuestra lista de alternativas seguras a methoxydiglycol según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.