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¿Debo evitar m-phenylenediamine durante el embarazo? | VeriMom

CIR’s safety review (1997 summary) reports one animal study with fetal deaths (other studies negative) and identifies measurable percutaneous absorption and metabolites — this supports a “suspected” reproductive hazard (h=2) rather than confirmed teratogen. No well‑characterised reproductive mechanism was found, only limited mechanistic data (hence m=1). Dermal absorption from hair‑dye use is reported as low but measurable, so exposure from typical topical cosmetic use is scored e=1. (Sources: CIR summary/CosmeticsInfo; PubMed animal study; ECHA registration dossier.)

ECHA regulatory hazard statements

  • H341
  • H331
  • H311
  • H301
  • H319
  • H317
  • H400
  • H410

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es m-phenylenediamine seguro durante el embarazo?
CIR’s safety review (1997 summary) reports one animal study with fetal deaths (other studies negative) and identifies measurable percutaneous absorption and metabolites — this supports a “suspected” reproductive hazard (h=2) rather than confirmed teratogen. No well‑characterised reproductive mechanism was found, only limited mechanistic data (hence m=1). Dermal absorption from hair‑dye use is reported as low but measurable, so exposure from typical topical cosmetic use is scored e=1. (Sources: CIR summary/CosmeticsInfo; PubMed animal study; ECHA registration dossier.)
¿Es m-phenylenediamine seguro durante la lactancia?
There are no robust human breastfeeding studies identified. The same animal evidence (fetal death in at least one study) and CIR finding of measurable dermal absorption support a conservative ‘suspected’ hazard for reproductive/developmental endpoints (h=2) and a theoretical mechanism only (m=1). Dermal exposure during use (hair dyes) is low but measurable (e=1); transfer into breastmilk was not specifically documented in available sources. (Sources: CIR summary/CosmeticsInfo; PubMed study; ECHA dossier.)
¿Es m-phenylenediamine seguro para la piel del bebé?
Hazard (h) and mechanism (m) are unchanged because no infant‑specific reproductive mechanism data were found. Adult dermal absorption is measurable; per instructions, increase exposure score by +1 for 0–3‑year‑old skin when absorption is measurable — adult e=1 → baby e=2. No infant‑specific dermal absorption or toxicokinetic studies were located. (Sources: CIR summary/CosmeticsInfo; ECHA registration; guidance on absorption in CIR review.)
¿Cómo puntúa VeriMom a m-phenylenediamine?
VeriMom puntúa m-phenylenediamine en 27/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a m-phenylenediamine en el embarazo?
Consulta nuestra lista de alternativas seguras a m-phenylenediamine según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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