¿Debo evitar ibuprofen durante el embarazo? | VeriMom
Ibuprofen (CAS 15687-27-1) is an NSAID with human/animal evidence of adverse fetal effects (fetal renal dysfunction/oligohydramnios and premature ductus arteriosus closure) prompting an FDA warning to avoid NSAID use at ≈20 weeks gestation and later; this supports a 'suspected' reproductive hazard (h=2). The mechanism is demonstrated (prostaglandin inhibition → fetal renal/ductus arteriosus effects), so m=2. Topical/cosmetic use yields low but measurable systemic exposure vs oral use, so exposure for topical cosmetic use is low (e=1). Sources: FDA, MotherToBaby/NCBI, ECHA substance information.
ECHA regulatory hazard statements
- •H360
- •H361
- •H362
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es ibuprofen seguro durante el embarazo?
- Ibuprofen (CAS 15687-27-1) is an NSAID with human/animal evidence of adverse fetal effects (fetal renal dysfunction/oligohydramnios and premature ductus arteriosus closure) prompting an FDA warning to avoid NSAID use at ≈20 weeks gestation and later; this supports a 'suspected' reproductive hazard (h=2). The mechanism is demonstrated (prostaglandin inhibition → fetal renal/ductus arteriosus effects), so m=2. Topical/cosmetic use yields low but measurable systemic exposure vs oral use, so exposure for topical cosmetic use is low (e=1). Sources: FDA, MotherToBaby/NCBI, ECHA substance information.
- ¿Es ibuprofen seguro durante la lactancia?
- Available clinical guidance and reviews indicate very low transfer of ibuprofen into human milk and no documented infant harm for usual maternal doses; therefore no reproductive/breastfeeding hazard is indicated (h=0, m=0). Milk transfer is measurable but low, so e=1. Sources: MotherToBaby (NCBI), NHS Specialist Pharmacy Service; clinical references note ibuprofen is generally compatible with breastfeeding.
- ¿Es ibuprofen seguro para la piel del bebé?
- Hazard (h=2) is carried over because systemic reproductive/toxicity evidence for ibuprofen exists (see pregnancy summary). Per instructions, infant-specific hazard or mechanism were not found so h and m are not increased beyond adult evidence (m=2). Topical exposure for infants is increased relative to adults (immature barrier and higher surface-area-to-weight) so exposure is raised by +1 (adult e=1 → baby e=2). No infant-specific studies were found showing different hazard; precautionary higher exposure score applied.
- ¿Cómo puntúa VeriMom a ibuprofen?
- VeriMom puntúa ibuprofen en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a ibuprofen en el embarazo?
- Consulta nuestra lista de alternativas seguras a ibuprofen según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.