VeriMom¿Debo evitar hydroxyanasatil retinoate durante el embarazo? | VeriMom
No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).
ECHA regulatory hazard statements
- •H360
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FAQ
- ¿Es hydroxyanasatil retinoate seguro durante el embarazo?
- No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).
- ¿Es hydroxyanasatil retinoate seguro durante la lactancia?
- Same structural/class‑based concern applies for breastfeeding: no specific reproductive/lactation studies found for this CAS, but retinoids have a known RAR/RXR mechanism. Systemic exposure after topical use is expected to be low but potentially measurable; transfer into breast milk has not been reported for this specific substance. Therefore hazard = 1 (structural/class alert), mechanism = 3, exposure = 1 (low but measurable).
- ¿Es hydroxyanasatil retinoate seguro para la piel del bebé?
- Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier; for a retinoate with measurable absorption in adults we increase exposure by +1 for babies. There are no infant‑specific toxicity or dermal developmental studies for this CAS, so hazard remains a structural/class alert (h=1) and mechanism remains retinoid receptor activity (m=3). Exposure is scored moderate (e=2) for baby skin due to increased per‑kg uptake from topical application.
- ¿Cómo puntúa VeriMom a hydroxyanasatil retinoate?
- VeriMom puntúa hydroxyanasatil retinoate en 33/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a hydroxyanasatil retinoate en el embarazo?
- Consulta nuestra lista de alternativas seguras a hydroxyanasatil retinoate según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.