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¿Debo evitar hexane durante el embarazo? | VeriMom

n‑Hexane (CAS 110‑54‑3) is classified for reproductive toxicity as H361 (suspected of damaging fertility or the unborn child) in ECHA/CLP-related sources and is listed by California OEHHA (Proposition 65) for reproductive toxicity; animal (inhalation) studies (NTP and others) report reproductive/testicular effects, so reproductive hazard is 'suspected'. The mechanism is reasonably well supported in animals via metabolism to neuro- and gonadotoxic metabolites (e.g. 2,5‑hexanedione) rather than a classic developmental teratogen, so mechanism score = 2. For typical topical cosmetic use residual hexane exposure would be low (volatile, poorly water‑soluble, usually used as an extraction solvent and removed), so exposure score = 1. Sources: ECHA registration/classification material, NTP/PubMed inhalation studies, OEHHA Prop 65 listing, PubChem/EWG summaries.

ECHA regulatory hazard statements

  • H361F

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es hexane seguro durante el embarazo?
n‑Hexane (CAS 110‑54‑3) is classified for reproductive toxicity as H361 (suspected of damaging fertility or the unborn child) in ECHA/CLP-related sources and is listed by California OEHHA (Proposition 65) for reproductive toxicity; animal (inhalation) studies (NTP and others) report reproductive/testicular effects, so reproductive hazard is 'suspected'. The mechanism is reasonably well supported in animals via metabolism to neuro- and gonadotoxic metabolites (e.g. 2,5‑hexanedione) rather than a classic developmental teratogen, so mechanism score = 2. For typical topical cosmetic use residual hexane exposure would be low (volatile, poorly water‑soluble, usually used as an extraction solvent and removed), so exposure score = 1. Sources: ECHA registration/classification material, NTP/PubMed inhalation studies, OEHHA Prop 65 listing, PubChem/EWG summaries.
¿Es hexane seguro durante la lactancia?
Hazard and mechanism mirror pregnancy (H361 / animal reproductive/testicular effects; metabolite‑mediated toxicity). Hexane is lipophilic and volatile; however, for normal cosmetic use any residual amounts are expected to be low and systemic levels in the lactating parent would be low, so infant exposure via breastmilk from typical topical cosmetic use is likely low but not zero.
¿Es hexane seguro para la piel del bebé?
Hazard and mechanism remain as above (animal reproductive/testicular effects; metabolite‑mediated). Because infant skin (0–3 yr) has a higher surface‑area‑to‑weight ratio and an immature barrier, exposure score is increased by +1 relative to adults when measurable absorption is possible; therefore exposure = 2 for baby skin where residual hexane might be present (e.g., in extracts/absolutes).
¿Cómo puntúa VeriMom a hexane?
VeriMom puntúa hexane en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a hexane en el embarazo?
Consulta nuestra lista de alternativas seguras a hexane según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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