VeriMom¿Debo evitar ethyl pyrrolidone durante el embarazo? | VeriMom
N‑ethyl‑2‑pyrrolidone (NEP; CAS 2687‑91‑4) has a harmonised CLP classification Repr. 1B H360D (may damage the unborn child) in ECHA/EU documents, which mandates a high hazard score. Animal studies report developmental toxicity after oral dosing, and toxicokinetic data show placental/fetal exposure in rats. Topical cosmetic exposure would likely give low but measurable systemic absorption for an organic solvent, so exposure is scored as 1. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es ethyl pyrrolidone seguro durante el embarazo?
- N‑ethyl‑2‑pyrrolidone (NEP; CAS 2687‑91‑4) has a harmonised CLP classification Repr. 1B H360D (may damage the unborn child) in ECHA/EU documents, which mandates a high hazard score. Animal studies report developmental toxicity after oral dosing, and toxicokinetic data show placental/fetal exposure in rats. Topical cosmetic exposure would likely give low but measurable systemic absorption for an organic solvent, so exposure is scored as 1. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
- ¿Es ethyl pyrrolidone seguro durante la lactancia?
- Because NEP carries harmonised Repr. 1B H360D classification and shows demonstrated systemic and placental transfer in animal studies, the hazard for lactation is aligned with pregnancy (h=3). Mechanistic/tk data show systemic availability and metabolites in dam urine/blood; breastmilk transfer is not well characterized in humans but systemic presence supports potential exposure to nursing infants, so exposure is rated low but measurable for topical use. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
- ¿Es ethyl pyrrolidone seguro para la piel del bebé?
- Hazard and mechanism remain driven by the harmonised Repr. 1B classification and animal developmental/toxicokinetic data (h=3, m=2). Because infant skin (0–3 yr) has higher permeability and higher surface‑area‑to‑weight, exposure is increased by +1 relative to adults (adult e=1 → infant e=2) when there is measurable absorption. No infant‑specific safety data were found. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
- ¿Cómo puntúa VeriMom a ethyl pyrrolidone?
- VeriMom puntúa ethyl pyrrolidone en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a ethyl pyrrolidone en el embarazo?
- Consulta nuestra lista de alternativas seguras a ethyl pyrrolidone según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.