VeriMom¿Debo evitar cis-retinoic acid durante el embarazo? | VeriMom
13‑cis‑retinoic acid (isotretinoin, CAS 4759‑48‑2) is a well‑established human teratogen when given systemically (oral isotretinoin causes severe, characteristic birth defects) and is regulated as a pregnancy‑contraindicated retinoid; the teratogenic mechanism is well characterized via retinoic‑acid / retinoid receptor signalling. Topical use gives lower systemic exposure than oral dosing but measurable absorption has been reported for topical retinoids and regulatory guidance treats retinoic acid/isotretinoin as a pregnancy risk. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))
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FAQ
- ¿Es cis-retinoic acid seguro durante el embarazo?
- 13‑cis‑retinoic acid (isotretinoin, CAS 4759‑48‑2) is a well‑established human teratogen when given systemically (oral isotretinoin causes severe, characteristic birth defects) and is regulated as a pregnancy‑contraindicated retinoid; the teratogenic mechanism is well characterized via retinoic‑acid / retinoid receptor signalling. Topical use gives lower systemic exposure than oral dosing but measurable absorption has been reported for topical retinoids and regulatory guidance treats retinoic acid/isotretinoin as a pregnancy risk. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))
- ¿Es cis-retinoic acid seguro durante la lactancia?
- Oral isotretinoin is contraindicated in breastfeeding because of concern for systemic exposure to the infant; the biological mechanism (retinoid receptor activity) is the same as for pregnancy. For topical cosmetic use, systemic transfer into milk is expected to be low but not zero, so breastfeeding exposure is considered low but not negligible. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))
- ¿Es cis-retinoic acid seguro para la piel del bebé?
- There is no infant‑specific evidence that topical cis‑retinoic acid applied to baby skin produces developmental/teratogenic effects (do not upgrade h/m without direct data). However infant skin has higher absorption (immature barrier and higher surface‑area‑to‑weight), so exposure scoring is increased relative to adults if the ingredient is present or applied directly. Topical retinoids are generally discouraged on young children because of irritancy and potential systemic uptake. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/32643315/?utm_source=openai))
- ¿Cómo puntúa VeriMom a cis-retinoic acid?
- VeriMom puntúa cis-retinoic acid en 7/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a cis-retinoic acid en el embarazo?
- Consulta nuestra lista de alternativas seguras a cis-retinoic acid según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.