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¿Debo evitar basic blue 9 durante el embarazo? | VeriMom

Methylene blue (Basic Blue 9, CAS 61-73-4) is associated with documented fetal harm after intra‑amniotic exposure (case series of jejuno‑ileal/intestinal atresia and fetal death); regulatory/clinical sources note teratogenic risk and recommend avoiding intra‑amniotic use in pregnancy. ECHA record references a harmonised/suspected reproduction hazard (H361) for this substance, and clinical teratology reviews/monographs (UKTIS, StatPearls, PubMed case reports) describe the fetal risks. Topical cosmetic use would give low but measurable systemic exposure only, so pregnancy exposure from normal topical use is judged low but not zero. (Sources: ECHA substance info; UKTIS monograph; PubMed case reports; StatPearls.)

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es basic blue 9 seguro durante el embarazo?
Methylene blue (Basic Blue 9, CAS 61-73-4) is associated with documented fetal harm after intra‑amniotic exposure (case series of jejuno‑ileal/intestinal atresia and fetal death); regulatory/clinical sources note teratogenic risk and recommend avoiding intra‑amniotic use in pregnancy. ECHA record references a harmonised/suspected reproduction hazard (H361) for this substance, and clinical teratology reviews/monographs (UKTIS, StatPearls, PubMed case reports) describe the fetal risks. Topical cosmetic use would give low but measurable systemic exposure only, so pregnancy exposure from normal topical use is judged low but not zero. (Sources: ECHA substance info; UKTIS monograph; PubMed case reports; StatPearls.)
¿Es basic blue 9 seguro durante la lactancia?
There are no strong human data specifically about transfer into breast milk, but given systemic use can produce fetal/ neonatal effects and that methylene blue is systemically active, a conservative rating is maintained (suspected reproductive hazard). Clinical guidance cautions use in pregnancy; breastfeeding exposure potential is unknown but systemic maternal exposure could result in transfer—therefore exposure from typical topical cosmetic use is likely low but measurable. (Sources: UKTIS, StatPearls, PubMed case literature.)
¿Es basic blue 9 seguro para la piel del bebé?
Infant-specific evidence of increased sensitivity is lacking; however because the ingredient has measurable absorption in humans and is systemically active, the exposure score for baby skin is increased by +1 versus adult (immature barrier and higher surface‑area:weight). No infant‑topical studies showing unique teratogenicity were found, so hazard/mechanism scores are not increased beyond the pregnancy assessment. (Sources: PubMed case reports; UKTIS; general toxicology summaries.)
¿Cómo puntúa VeriMom a basic blue 9?
VeriMom puntúa basic blue 9 en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a basic blue 9 en el embarazo?
Consulta nuestra lista de alternativas seguras a basic blue 9 según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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