VeriMom¿Debo evitar acrolein durante el embarazo? | VeriMom
Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
ECHA regulatory hazard statements
- •H225
- •H330
- •H311
- •H300
- •H314
- •H400
- •H410
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es acrolein seguro durante el embarazo?
- Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
- ¿Es acrolein seguro durante la lactancia?
- Same hazard and mechanism considerations apply for lactation: animal reproductive/developmental effects and mechanistic evidence indicate a suspected reproductive hazard. For cosmetic topical use systemic absorption is expected to be low but measurable, so transfer into breastmilk could theoretically occur if significant systemic levels were reached, but typical cosmetic exposures are low.
- ¿Es acrolein seguro para la piel del bebé?
- Hazard and mechanism same as for adults (suspected reproductive/developmental hazard with demonstrated mitochondrial/oocyte effects). Exposure score is increased by +1 for infants (per your rule) because acrolein has measurable dermal effects (it is skin‑corrosive/irritant and a small reactive molecule) so infants’ higher surface‑area‑to‑weight and immature barrier raise likely systemic uptake from topical application above adult levels.
- ¿Cómo puntúa VeriMom a acrolein?
- VeriMom puntúa acrolein en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a acrolein en el embarazo?
- Consulta nuestra lista de alternativas seguras a acrolein según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.