VeriMom¿Debo evitar 2-hydroxyethyl picramic acid durante el embarazo? | VeriMom
ECHA lists a harmonised CLP classification for 2-hydroxyethyl picramic acid (Index No. 604-056-00-2, CAS 99610-72-7) including H361f (suspected of damaging fertility), which per EU harmonised CLP guidance is a Category 2 reproductive hazard (supports h=2). Peer-review/regulatory assessments (SCCS/CIR/IMAP/TGA summaries) report animal data and testicular effects, indicating a demonstrated reproductive mechanism (m=2). Topical exposure from hair-dye use is low but measurable (SCCS evaluated on-head limits such as 0.6% and concluded risk mainly from sensitisation), so exposure for pregnant adults from cosmetic use is assessed as low but measurable (e=1).
ECHA regulatory hazard statements
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es 2-hydroxyethyl picramic acid seguro durante el embarazo?
- ECHA lists a harmonised CLP classification for 2-hydroxyethyl picramic acid (Index No. 604-056-00-2, CAS 99610-72-7) including H361f (suspected of damaging fertility), which per EU harmonised CLP guidance is a Category 2 reproductive hazard (supports h=2). Peer-review/regulatory assessments (SCCS/CIR/IMAP/TGA summaries) report animal data and testicular effects, indicating a demonstrated reproductive mechanism (m=2). Topical exposure from hair-dye use is low but measurable (SCCS evaluated on-head limits such as 0.6% and concluded risk mainly from sensitisation), so exposure for pregnant adults from cosmetic use is assessed as low but measurable (e=1).
- ¿Es 2-hydroxyethyl picramic acid seguro durante la lactancia?
- Harmonised CLP H361f applies; regulatory reviews cite reproductive toxicity in animals (m=2) and harmonised classification carries to concerns for breastfeeding parents. Topical cosmetic use gives low but measurable exposure (SCCS on-head limits), so e=1 for lactating adults. There are no specific data showing transfer into breastmilk identified in the reviewed sources (data gap).
- ¿Es 2-hydroxyethyl picramic acid seguro para la piel del bebé?
- Hazard (H361f harmonised) and reported animal reproductive/testicular effects justify h=2 for infant-related concern under the requested scoring system. Mechanistic evidence from animal reproductive toxicology supports m=2. Because infant skin (0–3 yr) has a higher surface‑area:weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → infant e=2) where topically applied products or accidental exposure could occur. No infant-specific absorption studies were found. (See data gaps.)
- ¿Cómo puntúa VeriMom a 2-hydroxyethyl picramic acid?
- VeriMom puntúa 2-hydroxyethyl picramic acid en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a 2-hydroxyethyl picramic acid en el embarazo?
- Consulta nuestra lista de alternativas seguras a 2-hydroxyethyl picramic acid según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.