VeriMom¿Debo evitar 2-ethylhexanol durante el embarazo? | VeriMom
Animal developmental studies (NTP CD‑1 mouse developmental toxicity report and other GLP studies) report increased fetal skeletal variations/other developmental effects in mice following exposure, supporting a suspected reproductive/developmental hazard (h=2). A specific mechanistic pathway for reproductive effects is not well established in the literature (assigned m=1 for theoretical/partial mechanistic evidence). For typical topical cosmetic use dermal absorption is low but measurable (e=1), so systemic exposure from normal cosmetic use is expected to be low; however systemic maternal exposure caused the effects in high‑dose animal studies. Sources: NTP developmental study; EPA PPRTV summary; PubChem substance summary; ECHA registration dossier.
ECHA regulatory hazard statements
- •H361
- •H361D
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FAQ
- ¿Es 2-ethylhexanol seguro durante el embarazo?
- Animal developmental studies (NTP CD‑1 mouse developmental toxicity report and other GLP studies) report increased fetal skeletal variations/other developmental effects in mice following exposure, supporting a suspected reproductive/developmental hazard (h=2). A specific mechanistic pathway for reproductive effects is not well established in the literature (assigned m=1 for theoretical/partial mechanistic evidence). For typical topical cosmetic use dermal absorption is low but measurable (e=1), so systemic exposure from normal cosmetic use is expected to be low; however systemic maternal exposure caused the effects in high‑dose animal studies. Sources: NTP developmental study; EPA PPRTV summary; PubChem substance summary; ECHA registration dossier.
- ¿Es 2-ethylhexanol seguro durante la lactancia?
- Because animal developmental/reproductive evidence indicates suspected reproductive/developmental toxicity, breastfeeding was conservatively scored h=2 (suspected). There is no well‑documented human lactation/transfer data or well‑characterized mechanism (m=1). Dermal absorption from cosmetic use is low but measurable (e=1), implying low maternal systemic exposures and therefore low but non‑zero potential for milk transfer in the absence of direct human lactation data.
- ¿Es 2-ethylhexanol seguro para la piel del bebé?
- Hazard (h=2) is carried over because animal developmental studies indicate suspected developmental/reproductive effects; there is no infant‑specific evidence to change hazard or mechanism scores. Mechanistic information remains limited (m=1). Exposure score is increased by +1 for baby skin (e=2) because infant skin has higher surface‑area‑to‑weight and an immature barrier and 2‑ethylhexanol is a small, somewhat lipophilic alcohol with measurable dermal absorption in models, so infant dermal exposure is plausibly higher than adult topical use.
- ¿Cómo puntúa VeriMom a 2-ethylhexanol?
- VeriMom puntúa 2-ethylhexanol en 27/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a 2-ethylhexanol en el embarazo?
- Consulta nuestra lista de alternativas seguras a 2-ethylhexanol según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.