Стоит ли избегать chlorophene при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли chlorophene при беременности?

Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)

Безопасен ли chlorophene при грудном вскармливании?

Harmonised H361 (and related regulatory assessments) indicate suspected effects on fertility/development (h=2). Mechanistic and toxicology data from animal studies and in vitro mutagenicity support a demonstrated concern (m=2). For topical use, maternal systemic exposure is expected to be low but measurable (e=1); no reliable data were found documenting transfer into breastmilk, so exposure via breastmilk cannot be ruled out. Sources: ECHA CLP listing; NTP and other toxicology literature.

Безопасен ли chlorophene для кожи малыша?

Hazard is the same (h=2) because of the harmonised H361f and supporting animal/toxicology data. Mechanistic evidence from studies (mutagenicity/in vivo toxicity) supports m=2. Exposure score is increased by +1 for baby skin (adult e=1 → baby e=2) because chlorophene is a relatively lipophilic, absorbable phenolic antimicrobial (logP ≈4.3) and infants (0–3 yrs) have higher surface‑area‑to‑weight and an immature barrier, increasing per‑kg systemic exposure from topical application. No infant‑specific toxicokinetic or dermal absorption studies were identified. Sources: ECHA CLP; NTP/toxicology studies; product/physicochemical records.

Как VeriMom оценивает chlorophene?

VeriMom оценивает chlorophene в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы chlorophene при беременности?

См. наш список безопасных альтернатив chlorophene с аналогичной функцией и классификацией без известных рисков.