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HIGH RISK

Should I Avoid ammonium vanadate During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H361
  • H361D

Products containing ammonium vanadate — check your shelf

These products list ammonium vanadate on their INCI. If one is in your routine, consider swapping it during pregnancy.

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to ammonium vanadate | VeriMom

IngredientsPregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated

See also

FAQ

Is ammonium vanadate safe during pregnancy?
Animal and review literature report reproductive and developmental toxicity after maternal exposure to vanadium compounds including ammonium metavanadate (embryotoxicity, increased fetal mortality and malformations). ECHA REACH registration dossiers and published reviews summarize these findings. Harmonised CLP proposals/intentions have been recorded for ammonium trioxovanadate but a final Annex VI harmonised H360 classification was not found; however H361 (suspected) is reported in some chemical listings/SDS. Given animal evidence and regulatory dossiers, hazard = suspected (H361-level). Low but measurable systemic exposure is expected from topical use of inorganic vanadates (so exposure scoring =1).
Is ammonium vanadate safe while breastfeeding?
Vanadium compounds are reported to be systemically bioavailable after absorption and have shown developmental/offspring effects in animal studies; placental/transplacental transfer and systemic distribution have been reported for vanadates, supporting potential transfer into milk (mechanism demonstrated in animal work). Topical cosmetic use would likely give low but measurable systemic exposure (e=1). Therefore breastfeeding is assigned the same suspected reproductive/developmental concern (h=2, m=2).
Is ammonium vanadate safe for baby skin?
No infant-specific toxicity studies were identified. Parent compound (vanadium/vanadate) shows developmental toxicity in animals. Because infant skin has higher permeability/surface-area-to-weight, exposure score is increased by +1 (adult e=1 → baby e=2). Hazard and mechanism are not increased without infant-specific evidence, so h=2, m=2. Topical use on baby skin could therefore give greater relative exposure and is not recommended.
How does VeriMom score ammonium vanadate?
VeriMom scores ammonium vanadate at 20/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to ammonium vanadate?
See our curated list of pregnancy-safe alternatives to ammonium vanadate based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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