¿Debo evitar aminoguanidine bicarbonate durante el embarazo? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es aminoguanidine bicarbonate seguro durante el embarazo?

Harmonised EU classification for aminoguanidinium hydrogen carbonate (CAS 2582-30-1) lists Reproductive toxicity Category 1B (H360), which indicates presumed human reproductive toxicity (ECHA). Animal/experimental studies with aminoguanidine report fetal developmental effects in rodents (fetal toxicity, growth effects), and aminoguanidine is a biologically active iNOS inhibitor affecting nitric oxide pathways relevant to pregnancy, supporting a demonstrated mechanism. Topical cosmetic exposure would likely give low but measurable systemic exposure for adults (no data showing negligible/permanent non-absorption). ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))

¿Es aminoguanidine bicarbonate seguro durante la lactancia?

Because the substance has an EU harmonised classification as Repr.1B (H360), the hazard score for breastfeeding is aligned with pregnancy (h=3). The mechanism (iNOS inhibition; demonstrated biological activity) supports potential effects on reproductive/offspring endpoints; no specific lactation transfer data were found, so adult topical exposure is assumed to give low but measurable systemic levels absent formulation-specific data. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))

¿Es aminoguanidine bicarbonate seguro para la piel del bebé?

Harmonised Repr.1B classification (H360) applies irrespective of age; therefore hazard remains h=3 for infant skin contact. Mechanistic evidence (aminoguanidine biological activity) is applicable. Exposure rating is increased by +1 for baby skin because aminoguanidine is a small, water‑soluble molecule with measurable absorption potential; infant skin has higher absorption per weight, so exposure is likely moderate relative to adults in the absence of specific dermal absorption/formulation data. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))

¿Cómo puntúa VeriMom a aminoguanidine bicarbonate?

VeriMom puntúa aminoguanidine bicarbonate en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.

¿Cuáles son las alternativas seguras a aminoguanidine bicarbonate en el embarazo?

Consulta nuestra lista de alternativas seguras a aminoguanidine bicarbonate según función similar y clasificación sin riesgos conocidos.