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symphytum officinale leaf extract hamilelikte güvenli mi?

Comfrey (Symphytum officinale) extracts can contain 1,2‑unsaturated pyrrolizidine alkaloids (PAs) that have demonstrated hepatotoxicity, genotoxicity and reproductive/developmental toxicity in animal studies; European herbal authorities and other regulators advise avoiding comfrey in pregnancy because safety has not been established. Topical cosmetic use will generally give low but measurable systemic exposure unless the extract is certified PA‑free. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC6631335/?utm_source=openai))

İçerikler
symphytum officinale leaf extract
ORTA RISK
40
/100
0

Pregnancy-safe products containing symphytum officinale leaf extract

Hamilelikte symphytum officinale leaf extract yerine kullanılabilecek güvenli alternatifler | VeriMom

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Frequently asked questions

symphytum officinale leaf extract hamilelikte güvenli mi?
Comfrey (Symphytum officinale) extracts can contain 1,2‑unsaturated pyrrolizidine alkaloids (PAs) that have demonstrated hepatotoxicity, genotoxicity and reproductive/developmental toxicity in animal studies; European herbal authorities and other regulators advise avoiding comfrey in pregnancy because safety has not been established. Topical cosmetic use will generally give low but measurable systemic exposure unless the extract is certified PA‑free. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC6631335/?utm_source=openai))
symphytum officinale leaf extract emzirirken güvenli mi?
Regulatory monographs and reviews advise that comfrey use during lactation is not established as safe; PAs are the key hazard and have been associated with systemic toxicity in animals, so breastfeeding is not recommended unless the extract is guaranteed free of PAs. Topical cosmetic exposure is likely low but not zero. ([e-lactancia.org](https://www.e-lactancia.org/media/papers/Consuelda-EMA2009.pdf?utm_source=openai))
symphytum officinale leaf extract bebek cildi için güvenli mi?
Infant skin has higher surface‑area‑to‑weight and a less mature barrier; if the extract contains residual PAs there is a plausible risk because PAs are systemically toxic and infants are more vulnerable. Therefore exposure score for 0–3 y is increased by +1 compared with adults; absence of PA‑free certification would justify caution. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC6631335/?utm_source=openai))
VeriMom symphytum officinale leaf extract nasıl puanlıyor?
VeriMom symphytum officinale leaf extract'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 40/100 (orta risk) olarak puanlar.
Hamilelikte symphytum officinale leaf extract yerine neler kullanılabilir?
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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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