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pueraria lobata root extract hamilelikte güvenli mi?

Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).

İçerikler
pueraria lobata root extract
ORTA RISK
40
/100
0

Hamilelikte pueraria lobata root extract yerine kullanılabilecek güvenli alternatifler | VeriMom

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Frequently asked questions

pueraria lobata root extract hamilelikte güvenli mi?
Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).
pueraria lobata root extract emzirirken güvenli mi?
Same hazard and mechanism apply for lactating people because the active constituents are phytoestrogens with demonstrated endocrine activity in animals/in vitro. Topical application to the breast would give low but measurable exposure to the parent; systemic transfer into milk is plausible for small lipophilic isoflavones but direct human lactation data are lacking, so exposure is rated low (e=1). Animal reproductive/lactation-specific data are limited. See cited animal and in vitro studies.
pueraria lobata root extract bebek cildi için güvenli mi?
Hazard and mechanism remain 'suspected' (h=2/m=2) because the extract contains phytoestrogens shown to have reproductive effects in animals and estrogenic activity in vitro. Absorption concern is increased for infants (immature skin barrier and higher surface‑area‑to‑weight); therefore exposure is increased by +1 to e=2 even though absolute dermal absorption data for the extract are limited. No infant‑specific toxicity studies were identified.
VeriMom pueraria lobata root extract nasıl puanlıyor?
VeriMom pueraria lobata root extract'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 40/100 (orta risk) olarak puanlar.
Hamilelikte pueraria lobata root extract yerine neler kullanılabilir?
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Tıbbi Sorumluluk Reddi

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