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piroctone olamine hamilelikte güvenli mi?

No harmonised reproductive classification was found for piroctone olamine (CAS 68890-66-4); an oral reproduction study in rats showed adverse offspring growth only at high oral doses with a systemic NOAEL of 10 mg/kg/day and reproductive parameters unaffected up to 250 mg/kg/day (animal data). Regulatory/ingredient databases and EWG list it as used in cosmetics with no pregnancy-specific bans. For topical cosmetic use in pregnancy expected systemic exposure is low but measurable, so exposure score =1. Sources: PubMed rat reproduction study and ECHA registration/registry entries and EWG summary.

İçerikler
piroctone olamine
BILINEN RISK YOK
93
/100
0

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Frequently asked questions

piroctone olamine hamilelikte güvenli mi?
No harmonised reproductive classification was found for piroctone olamine (CAS 68890-66-4); an oral reproduction study in rats showed adverse offspring growth only at high oral doses with a systemic NOAEL of 10 mg/kg/day and reproductive parameters unaffected up to 250 mg/kg/day (animal data). Regulatory/ingredient databases and EWG list it as used in cosmetics with no pregnancy-specific bans. For topical cosmetic use in pregnancy expected systemic exposure is low but measurable, so exposure score =1. Sources: PubMed rat reproduction study and ECHA registration/registry entries and EWG summary.
piroctone olamine emzirirken güvenli mi?
No clinical or human lactation studies or harmonised classification indicating developmental/teratogenic risk were identified. Dermal cosmetic use is expected to give low systemic exposure; milk transfer data are not available, so exposure is conservatively scored as low but measurable (e=1). Animal oral reproduction study did not demonstrate reproductive toxicity at moderate doses (see PubMed).
piroctone olamine bebek cildi için güvenli mi?
No infant-specific evidence of reproductive or developmental hazard. Dermal absorption for adults is reported to be very low in supplier/regulatory dossiers; however immature infant skin has higher absorption potential, so exposure is increased by +1 (adult e=1→baby e=2). There is no infant-specific toxicity data to change hazard or mechanism scores.
VeriMom piroctone olamine nasıl puanlıyor?
VeriMom piroctone olamine'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 93/100 (bilinen risk yok) olarak puanlar.
Hamilelikte piroctone olamine yerine neler kullanılabilir?
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