glycyrrhetinic acid hamilelikte güvenli mi?

Hamilelikte glycyrrhetinic acid yerine kullanılabilecek güvenli alternatifler | VeriMom

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Frequently asked questions

glycyrrhetinic acid hamilelikte güvenli mi?

Glycyrrhetinic acid is not listed in EU Annex II/III nor has a harmonised reproductive classification, but multiple human and mechanistic studies show it inhibits placental 11β‑HSD2 and maternal licorice (glycyrrhizin → glycyrrhetinic acid) intake is associated with adverse fetal/neurodevelopmental outcomes — supporting a 'suspected' reproductive hazard. ([echa.europa.eu](https://echa.europa.eu/substance-information/-/substanceinfo/100.006.769?utm_source=openai))

glycyrrhetinic acid emzirirken güvenli mi?

No harmonised CLP reproductive/teratogenic classification was found; however the demonstrated mechanism (11β‑HSD2 inhibition) is relevant to glucocorticoid exposure. Systemic transfer to breastmilk after topical use is expected to be low but measurable if significant percutaneous absorption occurs. ([echa.europa.eu](https://echa.europa.eu/substance-information/-/substanceinfo/100.006.769?utm_source=openai))

glycyrrhetinic acid bebek cildi için güvenli mi?

There is no infant‑specific evidence of teratogenicity from topical use, but because glycyrrhetinic acid has demonstrated biological activity (11β‑HSD2 inhibition) and infant skin has higher absorption per kg, exposure score is increased for 0–3 yr. No EU ban/restriction was identified for topical cosmetic use. ([echa.europa.eu](https://echa.europa.eu/substance-information/-/substanceinfo/100.006.769?utm_source=openai))

VeriMom glycyrrhetinic acid nasıl puanlıyor?

VeriMom glycyrrhetinic acid'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 40/100 (orta risk) olarak puanlar.

Hamilelikte glycyrrhetinic acid yerine neler kullanılabilir?

Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.