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darutoside hamilelikte güvenli mi?

Animal evidence: an experimental rat study reported that darutoside caused termination of early pregnancy at 20–40 mg/kg, indicating a suspected reproductive/abortifacient effect in animals (PubMed). No harmonised CLP classification, SCCS opinion, or CIR safety assessment for darutoside was found to contradict this, so the animal finding drives a 'suspected' score. Topical cosmetic use likely gives low but measurable systemic exposure (glycoside, used at low % in formulations), so exposure rated low (e=1).

İçerikler
darutoside
ORTA RISK
47
/100
0

Pregnancy-safe products containing darutoside

Hamilelikte darutoside yerine kullanılabilecek güvenli alternatifler | VeriMom

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Frequently asked questions

darutoside hamilelikte güvenli mi?
Animal evidence: an experimental rat study reported that darutoside caused termination of early pregnancy at 20–40 mg/kg, indicating a suspected reproductive/abortifacient effect in animals (PubMed). No harmonised CLP classification, SCCS opinion, or CIR safety assessment for darutoside was found to contradict this, so the animal finding drives a 'suspected' score. Topical cosmetic use likely gives low but measurable systemic exposure (glycoside, used at low % in formulations), so exposure rated low (e=1).
darutoside emzirirken güvenli mi?
No data on transfer into human milk or lactation-specific studies were found; the same animal reproductive signal supports a suspected hazard (h=2) but there is no demonstrated mechanism of milk transfer. Dermal/topical use would likely result in low but potentially measurable systemic exposure in adults (e=1).
darutoside bebek cildi için güvenli mi?
No infant-specific toxicology available. Per your guidance, because darutoside shows an animal reproductive effect and topical use has measurable absorption in adults, baby skin exposure is increased by +1 (adult e=1 → baby e=2) to account for immature barrier and higher surface-area-to-weight; hazard and mechanism scores are not increased without infant-specific evidence. No regulatory body (harmonised CLP, SCCS, CIR) provides a contrary safety opinion. (See sources below.)
VeriMom darutoside nasıl puanlıyor?
VeriMom darutoside'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 47/100 (orta risk) olarak puanlar.
Hamilelikte darutoside yerine neler kullanılabilir?
Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.

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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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