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chrysanthemum parthenium extract hamilelikte güvenli mi?

Feverfew (Chrysanthemum/Tanacetum parthenium) extracts contain the sesquiterpene lactone parthenolide, which has demonstrated biological activity (including uterine-stimulant/emmenagogue effects in traditional reports and embryo toxicity in an in vitro embryoculture screening) and is the basis for recommendations to avoid use in pregnancy; therefore reproductive hazard is scored as suspected (h=2). Evidence: a reproductive screening study and recent reviews note embryo toxicity signals and advise avoidance in pregnancy. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/16781113/?utm_source=openai))

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chrysanthemum parthenium extract
ORTA RISK
40
/100
0

Hamilelikte chrysanthemum parthenium extract yerine kullanılabilecek güvenli alternatifler | VeriMom

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chrysanthemum parthenium extract hamilelikte güvenli mi?
Feverfew (Chrysanthemum/Tanacetum parthenium) extracts contain the sesquiterpene lactone parthenolide, which has demonstrated biological activity (including uterine-stimulant/emmenagogue effects in traditional reports and embryo toxicity in an in vitro embryoculture screening) and is the basis for recommendations to avoid use in pregnancy; therefore reproductive hazard is scored as suspected (h=2). Evidence: a reproductive screening study and recent reviews note embryo toxicity signals and advise avoidance in pregnancy. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/16781113/?utm_source=openai))
chrysanthemum parthenium extract emzirirken güvenli mi?
There are no data on excretion of feverfew constituents into human milk; reviews and monographs state safety in lactation is unknown and recommend avoidance. Given the lack of direct data but the presence of active constituents (parthenolide) and traditional contraindication, this is scored as a low/suspected concern (h=1) with a theoretical mechanism (m=1). ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30000921/?utm_source=openai))
chrysanthemum parthenium extract bebek cildi için güvenli mi?
No infant-specific reproductive hazard data were identified; reproductive hazard scores are not increased for infants. Topical exposure absorption is measurable for botanical extracts and infants have higher skin absorption, so exposure is increased by +1 (adult e=1 → infant e=2). Note: feverfew/parthenolide is a known skin sensitizer in some people (contact dermatitis) which is a non‑reproductive safety concern for infants. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/19112586/?utm_source=openai))
VeriMom chrysanthemum parthenium extract nasıl puanlıyor?
VeriMom chrysanthemum parthenium extract'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 40/100 (orta risk) olarak puanlar.
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