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carum petroselinum seed oil hamilelikte güvenli mi?

Carum petroselinum (parsley) seed/extract (CAS 84012-33-9) is listed with a RESTRICTION in the EU Official Journal / CosIng (Annex III-type listing for extracts), and the literature identifies apiol (a major constituent of parsley seed oil) as an abortifacient with animal and historical human evidence; these facts support a ‘suspected’ reproductive hazard and a demonstrated uterotonic/embryotoxic mechanism. Topical cosmetic use gives low but measurable dermal exposure for typical formulations (essential oils / volatile oils are lipophilic and can be absorbed), so exposure is judged low (e=1).

İçerikler
carum petroselinum seed oil
ORTA RISK
40
/100
0

Hamilelikte carum petroselinum seed oil yerine kullanılabilecek güvenli alternatifler | VeriMom

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carum petroselinum seed oil hamilelikte güvenli mi?
Carum petroselinum (parsley) seed/extract (CAS 84012-33-9) is listed with a RESTRICTION in the EU Official Journal / CosIng (Annex III-type listing for extracts), and the literature identifies apiol (a major constituent of parsley seed oil) as an abortifacient with animal and historical human evidence; these facts support a ‘suspected’ reproductive hazard and a demonstrated uterotonic/embryotoxic mechanism. Topical cosmetic use gives low but measurable dermal exposure for typical formulations (essential oils / volatile oils are lipophilic and can be absorbed), so exposure is judged low (e=1).
carum petroselinum seed oil emzirirken güvenli mi?
No specific harmonised CLP or SCCS/CIR safety assessment for lactation was found, but the same constituent (apiol) that is linked to reproductive effects could theoretically be transferred if systemic absorption occurred; because direct data on milk transfer are lacking, mechanism is graded as theoretical-to-plausible (m=1) but hazard is kept at suspected (h=2) due to the reproductive/abortifacient evidence. Dermal exposure from cosmetics is expected to be low (e=1).
carum petroselinum seed oil bebek cildi için güvenli mi?
No infant-specific toxicokinetic studies were located; baby skin exposure is increased relative to adults because essential oils / volatile oils are measurably absorbable and infants have higher surface-area-to-weight and immature barrier. Per your rules, exposure is raised by +1 (adult e=1 → infant e=2). Hazard and mechanism are not increased absent infant-specific evidence. Avoid direct application to infant skin and products intended for babies unless formulation data show absence of apiol/alkenylbenzenes.
VeriMom carum petroselinum seed oil nasıl puanlıyor?
VeriMom carum petroselinum seed oil'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 40/100 (orta risk) olarak puanlar.
Hamilelikte carum petroselinum seed oil yerine neler kullanılabilir?
Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.

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Tıbbi Sorumluluk Reddi

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