VeriMomammonium glycyrrhizate hamilelikte güvenli mi?
CIR’s final safety assessment includes ammonium glycyrrhizate and judges cosmetic use acceptable with typical use conditions, but independent human/epidemiological and toxicology assessments link glycyrrhizic/glycyrrhetinic acids (parent compounds) with pregnancy outcomes after oral exposure via inhibition of placental 11β‑HSD2 and associated fetal effects; therefore reproductive concern is suspected (h=2) with a demonstrated mechanism (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure score is 1. (Sources: CIR final report; VKM risk assessment; PBPK and human studies summarized in LactMed and literature).
Hamilelikte ammonium glycyrrhizate yerine kullanılabilecek güvenli alternatifler | VeriMom
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Frequently asked questions
- ammonium glycyrrhizate hamilelikte güvenli mi?
- CIR’s final safety assessment includes ammonium glycyrrhizate and judges cosmetic use acceptable with typical use conditions, but independent human/epidemiological and toxicology assessments link glycyrrhizic/glycyrrhetinic acids (parent compounds) with pregnancy outcomes after oral exposure via inhibition of placental 11β‑HSD2 and associated fetal effects; therefore reproductive concern is suspected (h=2) with a demonstrated mechanism (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure score is 1. (Sources: CIR final report; VKM risk assessment; PBPK and human studies summarized in LactMed and literature).
- ammonium glycyrrhizate emzirirken güvenli mi?
- Glycyrrhizic acid (parent) has been detected in breastmilk after maternal oral intake and systemic effects are reported with ingestion; mechanism (11β‑HSD2 inhibition and systemic glycyrrhetinic metabolites) is demonstrated. For topical cosmetic use transfer to milk from topical use is unlikely but possible at low measurable levels, so exposure =1 and hazard =2 pending significant systemic exposure. (Sources: LactMed/NCBI; CIR; VKM).
- ammonium glycyrrhizate bebek cildi için güvenli mi?
- No infant‑specific topical hazard data found; hazard and mechanism remain linked to the parent glycyrrhizic/glycyrrhetinic acids (h=2, m=2). Because infant skin has higher per‑kg absorption, raise exposure by +1 compared with adults (adult e=1 → infant e=2) when the ingredient shows measurable absorption. No evidence supports increasing hazard or mechanism scores for infants in the absence of infant‑specific toxicology. (Sources: CIR; VKM; LactMed).
- VeriMom ammonium glycyrrhizate nasıl puanlıyor?
- VeriMom ammonium glycyrrhizate'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 40/100 (orta risk) olarak puanlar.
- Hamilelikte ammonium glycyrrhizate yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.