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7-dehydrocholesterol hamilelikte güvenli mi?

No harmonised CLP reproductive classification (ECHA brief profile shows registrations/self‑notifications but no Annex VI harmonised classification) and no SCCS/CIR reproductive safety restriction found. 7‑DHC is an endogenous cholesterol/vitamin D3 precursor; peer‑reviewed studies describe its role and that elevated systemic 7‑DHC is associated with genetic DHCR7 defects (Smith‑Lemli‑Opitz syndrome) or drug inhibition of DHCR7, but there is no evidence that topical cosmetic use of 7‑DHC causes reproductive toxicity in pregnant humans or animals. Topical absorption is possible for a lipophilic sterol but expected to be low, so exposure score = 1. (Sources: ECHA brief profile; PubMed sterol/7‑DHC studies; EWG ingredient page).

İçerikler
7-dehydrocholesterol
BILINEN RISK YOK
93
/100
0

Pregnancy-safe products containing 7-dehydrocholesterol

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Frequently asked questions

7-dehydrocholesterol hamilelikte güvenli mi?
No harmonised CLP reproductive classification (ECHA brief profile shows registrations/self‑notifications but no Annex VI harmonised classification) and no SCCS/CIR reproductive safety restriction found. 7‑DHC is an endogenous cholesterol/vitamin D3 precursor; peer‑reviewed studies describe its role and that elevated systemic 7‑DHC is associated with genetic DHCR7 defects (Smith‑Lemli‑Opitz syndrome) or drug inhibition of DHCR7, but there is no evidence that topical cosmetic use of 7‑DHC causes reproductive toxicity in pregnant humans or animals. Topical absorption is possible for a lipophilic sterol but expected to be low, so exposure score = 1. (Sources: ECHA brief profile; PubMed sterol/7‑DHC studies; EWG ingredient page).
7-dehydrocholesterol emzirirken güvenli mi?
No evidence that topical 7‑DHC is a reproductive toxicant or that it produces adverse effects via breastmilk. Mechanistic/reproductive hazards are associated with systemic elevation of 7‑DHC caused by genetic DHCR7 deficiency or certain drugs that inhibit DHCR7, not by topical application. Systemic absorption from typical topical cosmetic use is expected to be low but measurable (e=1).
7-dehydrocholesterol bebek cildi için güvenli mi?
No infant‑specific studies showing reproductive or developmental toxicity from topical 7‑DHC. Because 7‑DHC is a skin sterol/provitamin D3 present endogenously and topical absorption of lipophilic sterols is measurable, infant exposure via skin is higher than adults (immature barrier and higher surface‑area:weight), so exposure score is increased by +1 (adult e=1 → baby e=2). No evidence found that baby skin exposure causes harm at cosmetic use levels; however systemic elevation of 7‑DHC from DHCR7 disruption is a known hazard in genetic disease and medication interactions (not a topical‑cosmetic finding).
VeriMom 7-dehydrocholesterol nasıl puanlıyor?
VeriMom 7-dehydrocholesterol'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 93/100 (bilinen risk yok) olarak puanlar.
Hamilelikte 7-dehydrocholesterol yerine neler kullanılabilir?
Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.

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