VeriMomHamilelikte tetrahydrofurfuryl methacrylate kullanmaktan kaçınmalı mıyım? | VeriMom
Tetrahydrofurfuryl methacrylate (CAS 2455-24-5) has a harmonised CLP classification Repr. 1A H360Df (may damage fertility and the unborn child), which is legally binding in the EU and places it in CMR Category 1A; by calibration H360 => h=3. No well-characterized molecular mechanism for reproductive toxicity was found in public dossiers or the literature, so mechanism is scored as theoretical/unknown (m=1). For topical cosmetic exposure, dermal absorption is plausible (log Pow ≈1.8 and it's a low-molecular weight methacrylate) but not extremely high, so exposure is scored as low but measurable (e=1). Sources: EU delegated regulation / harmonised CLP listing and ECHA materials.
ECHA regulatory hazard statements
- •H360DF
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- tetrahydrofurfuryl methacrylate hamilelikte güvenli mi?
- Tetrahydrofurfuryl methacrylate (CAS 2455-24-5) has a harmonised CLP classification Repr. 1A H360Df (may damage fertility and the unborn child), which is legally binding in the EU and places it in CMR Category 1A; by calibration H360 => h=3. No well-characterized molecular mechanism for reproductive toxicity was found in public dossiers or the literature, so mechanism is scored as theoretical/unknown (m=1). For topical cosmetic exposure, dermal absorption is plausible (log Pow ≈1.8 and it's a low-molecular weight methacrylate) but not extremely high, so exposure is scored as low but measurable (e=1). Sources: EU delegated regulation / harmonised CLP listing and ECHA materials.
- tetrahydrofurfuryl methacrylate emzirirken güvenli mi?
- Harmonised classification H360Df (Repr. 1A) applies to reproductive/developmental hazards; per your scoring rules H360 => h=3 for breastfeeding context as well. Mechanistic data for transfer into human milk or a distinct lactation-specific mechanism were not identified (m=1). Dermal exposure during lactation is possible and considered low but measurable (e=1).
- tetrahydrofurfuryl methacrylate bebek cildi için güvenli mi?
- Because the substance carries harmonised H360Df (CMR Cat 1A) the hazard score for infant skin is h=3 (harmonised CMR overrides). No infant-specific mechanistic data were located (m=1). Exposure for babies (0–3 yr) is increased relative to adults due to immature skin barrier and higher surface-area-to-weight; adult exposure was scored e=1 so infant exposure is increased by +1 → e=2. No infant-specific absorption or toxicokinetic studies were found that would change hazard or mechanism scores.
- VeriMom tetrahydrofurfuryl methacrylate nasıl puanlıyor?
- VeriMom tetrahydrofurfuryl methacrylate'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 27/100 (yüksek risk) olarak puanlar.
- Hamilelikte tetrahydrofurfuryl methacrylate yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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