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HIGH RISK

Hamilelikte silybum marianum fruit extract kullanmaktan kaçınmalı mıyım? | VeriMom

No EU harmonised classification (CLH) for CAS 84604-20-6 was identified on ECHA substance pages, though some supplier SDS for concentrated silymarin list H361 (self-classified). Peer-reviewed animal studies and reviews report no clear reproductive/developmental toxicity and in some cases protective effects of silymarin. Given the lack of harmonised H360/H361 CLH and the presence of supplier H361 self-classifications, hazard is scored as 1 (class/structural concern/self-notifications noted). (Sources: ECHA substance/registration pages; supplier SDS; PubMed review and animal study).

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

silybum marianum fruit extract hamilelikte güvenli mi?
No EU harmonised classification (CLH) for CAS 84604-20-6 was identified on ECHA substance pages, though some supplier SDS for concentrated silymarin list H361 (self-classified). Peer-reviewed animal studies and reviews report no clear reproductive/developmental toxicity and in some cases protective effects of silymarin. Given the lack of harmonised H360/H361 CLH and the presence of supplier H361 self-classifications, hazard is scored as 1 (class/structural concern/self-notifications noted). (Sources: ECHA substance/registration pages; supplier SDS; PubMed review and animal study).
silybum marianum fruit extract emzirirken güvenli mi?
Same rationale as pregnancy: no harmonised CLH; limited animal data do not show developmental harm and may indicate protective effects. Topical cosmetic use would give low systemic exposure for the lactating parent, so breastfeeding hazard scored 1 (precaution due to self-classed H361 on some SDS and active flavonolignan content).
silybum marianum fruit extract bebek cildi için güvenli mi?
Ingredient is a botanical extract (skin-conditioning/antioxidant). Adult topical absorption is expected to be low; however per instruction baby exposure score is increased by +1 because infant skin barrier is immature. No infant-specific toxicity data were found. Therefore hazard/mechanism same as adult (1), exposure increased to 2 for 0–3 y/o. (Sources: CosIng listings, EWG Skin Deep, PubMed literature).
VeriMom silybum marianum fruit extract nasıl puanlıyor?
VeriMom silybum marianum fruit extract'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 27/100 (yüksek risk) olarak puanlar.
Hamilelikte silybum marianum fruit extract yerine neler kullanılabilir?
Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.

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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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