Hamilelikte retinoic acid kullanmaktan kaçınmalı mıyım? | VeriMom
All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- retinoic acid hamilelikte güvenli mi?
- All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
- retinoic acid emzirirken güvenli mi?
- Direct data on excretion of topical tretinoin into human milk are limited/ inconclusive, but the compound is systemically active and a retinoid; because of systemic teratogenicity and potential for transfer, caution is advised. Systemic absorption from topical use is generally low, so breast‑milk exposure is likely low but not well‑quantified in humans. (ECHA; FDA/label information; limited pharmacokinetic studies).
- retinoic acid bebek cildi için güvenli mi?
- Tretinoin is a known teratogenic retinoid with well‑defined RAR/RXR activity. Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, so exposure score is increased by +1 relative to adults when topical absorption is measurable. Because tretinoin is prohibited in cosmetics in the EU and flagged as H360, it is not appropriate for use on infant skin. (ECHA; SCCS/CIR context; pediatric exposure considerations).
- VeriMom retinoic acid nasıl puanlıyor?
- VeriMom retinoic acid'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 13/100 (yüksek risk) olarak puanlar.
- Hamilelikte retinoic acid yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.