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HIGH RISK

Hamilelikte quaternium-15 kullanmaktan kaçınmalı mıyım? | VeriMom

Quaternium‑15 (CAS 4080‑31‑3 / mixed cis/trans and cis isomer CAS variants) has been regulated as a CMR (toxic for reproduction) concern in the EU and has been moved into Annex II (prohibited in cosmetics) following classification of the cis‑isomer as a reproductive toxicant; harmonised/authoritative sources and regulatory reviews report reproductive/teratogenic findings in animals. Because of that regulatory action (EU Annex II / Commission Regulation amending 1223/2009) and reported animal findings, the hazard score is 2. Mechanistically, quaternium‑15 is a formaldehyde‑releasing preservative and there are animal reproduction/developmental toxicity findings reported in regulatory reviews, so mechanism is scored as demonstrated (2). Topical cosmetic exposures give low but measurable systemic exposure for most formaldehyde releasers, therefore exposure is scored 1 for pregnancy. (Sources: EU Commission Regulation / Annex II amendment; SCCS/CIR/regulatory reviews; animal studies.)

ECHA regulatory hazard statements

  • H361
  • H361D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

quaternium-15 hamilelikte güvenli mi?
Quaternium‑15 (CAS 4080‑31‑3 / mixed cis/trans and cis isomer CAS variants) has been regulated as a CMR (toxic for reproduction) concern in the EU and has been moved into Annex II (prohibited in cosmetics) following classification of the cis‑isomer as a reproductive toxicant; harmonised/authoritative sources and regulatory reviews report reproductive/teratogenic findings in animals. Because of that regulatory action (EU Annex II / Commission Regulation amending 1223/2009) and reported animal findings, the hazard score is 2. Mechanistically, quaternium‑15 is a formaldehyde‑releasing preservative and there are animal reproduction/developmental toxicity findings reported in regulatory reviews, so mechanism is scored as demonstrated (2). Topical cosmetic exposures give low but measurable systemic exposure for most formaldehyde releasers, therefore exposure is scored 1 for pregnancy. (Sources: EU Commission Regulation / Annex II amendment; SCCS/CIR/regulatory reviews; animal studies.)
quaternium-15 emzirirken güvenli mi?
Same hazard/mechanism as for pregnancy (regulatory classification and animal data). With typical topical cosmetic use, systemic absorption is expected to be low; therefore breastmilk exposure potential is low but not zero — exposure scored 1. No specific breast‑milk transfer studies located in the reviewed sources.
quaternium-15 bebek cildi için güvenli mi?
Hazard and mechanism remain driven by the same regulatory and animal evidence (EU prohibition based on CMR classification of the cis‑isomer and reported developmental toxicity). Exposure score is increased by +1 for infants (per instruction) because infant skin barrier immaturity and higher surface‑area‑to‑weight ratio make low but measurable percutaneous absorption more relevant; therefore baby exposure scored 2. Note: quaternium‑15 is also a known skin sensitizer in humans, increasing concern for infant dermal irritation/allergy.
VeriMom quaternium-15 nasıl puanlıyor?
VeriMom quaternium-15'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 20/100 (yüksek risk) olarak puanlar.
Hamilelikte quaternium-15 yerine neler kullanılabilir?
Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.

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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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