VeriMomHamilelikte methylene di-t-butylcresol kullanmaktan kaçınmalı mıyım? | VeriMom
ECHA lists 6,6'-di-tert‑butyl‑2,2'‑methylenedi‑p‑cresol (CAS 119‑47‑1) with a harmonised classification for reproductive toxicity (Repr. 1B, H360F — “May damage fertility”), which by the scoring rules yields h=3. Animal reproductive/developmental findings are reported in regulatory dossiers (developmental NOAEL/LOAEL in non‑rodents in EPA/registration material), but a specific molecular reproductive mechanism is not established in the literature (m=1). For routine topical cosmetic use dermal absorption is likely low but not zero (lipophilic high‑molecular phenolic antioxidant), so exposure for a pregnant adult is scored as low but measurable (e=1). Sources: ECHA harmonised classification and registration/assessment data and regulatory toxicology summaries.
ECHA regulatory hazard statements
- •H360F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- methylene di-t-butylcresol hamilelikte güvenli mi?
- ECHA lists 6,6'-di-tert‑butyl‑2,2'‑methylenedi‑p‑cresol (CAS 119‑47‑1) with a harmonised classification for reproductive toxicity (Repr. 1B, H360F — “May damage fertility”), which by the scoring rules yields h=3. Animal reproductive/developmental findings are reported in regulatory dossiers (developmental NOAEL/LOAEL in non‑rodents in EPA/registration material), but a specific molecular reproductive mechanism is not established in the literature (m=1). For routine topical cosmetic use dermal absorption is likely low but not zero (lipophilic high‑molecular phenolic antioxidant), so exposure for a pregnant adult is scored as low but measurable (e=1). Sources: ECHA harmonised classification and registration/assessment data and regulatory toxicology summaries.
- methylene di-t-butylcresol emzirirken güvenli mi?
- Same harmonised reproductive classification (Repr. 1B, H360F) applies and supports a high hazard score (h=3). No clear mechanistic data specific to lactational transfer was found (m=1). For topical cosmetic use, maternal dermal exposure is expected to be low but measurable; breastmilk transfer is plausible for lipophilic compounds but was not documented in available studies, so exposure is scored as low (e=1). Regulatory guidance therefore flags this substance for reproductive concern.
- methylene di-t-butylcresol bebek cildi için güvenli mi?
- Hazard remains high because of the harmonised Repr.1B/H360F classification (h=3). No infant‑specific mechanism data was identified (m=1). Because infant skin (0–3 yr) has higher absorption per body weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → baby e=2) where dermal absorption is measurable. No infant dermal studies were located to justify changing hazard or mechanism scores.
- VeriMom methylene di-t-butylcresol nasıl puanlıyor?
- VeriMom methylene di-t-butylcresol'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 27/100 (yüksek risk) olarak puanlar.
- Hamilelikte methylene di-t-butylcresol yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.