VeriMomHamilelikte hydroxyanasatil retinoate kullanmaktan kaçınmalı mıyım? | VeriMom
No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).
ECHA regulatory hazard statements
- •H360
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FAQ
- hydroxyanasatil retinoate hamilelikte güvenli mi?
- No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).
- hydroxyanasatil retinoate emzirirken güvenli mi?
- Same structural/class‑based concern applies for breastfeeding: no specific reproductive/lactation studies found for this CAS, but retinoids have a known RAR/RXR mechanism. Systemic exposure after topical use is expected to be low but potentially measurable; transfer into breast milk has not been reported for this specific substance. Therefore hazard = 1 (structural/class alert), mechanism = 3, exposure = 1 (low but measurable).
- hydroxyanasatil retinoate bebek cildi için güvenli mi?
- Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier; for a retinoate with measurable absorption in adults we increase exposure by +1 for babies. There are no infant‑specific toxicity or dermal developmental studies for this CAS, so hazard remains a structural/class alert (h=1) and mechanism remains retinoid receptor activity (m=3). Exposure is scored moderate (e=2) for baby skin due to increased per‑kg uptake from topical application.
- VeriMom hydroxyanasatil retinoate nasıl puanlıyor?
- VeriMom hydroxyanasatil retinoate'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 33/100 (yüksek risk) olarak puanlar.
- Hamilelikte hydroxyanasatil retinoate yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.