Hamilelikte cyclamen aldehyde kullanmaktan kaçınmalı mıyım? | VeriMom
ECHA registration data and many supplier/SDS classifications list cyclamen aldehyde as Repr. Cat. 2 / H361 (suspected of damaging fertility or the unborn child) based on repeat-dose and reproductive findings in rats reported in the REACH dossier; however the published mechanistic work shows the male reproductive toxicity is tied to a species‑specific CoA‑conjugate metabolic pathway in rats. Topical cosmetic exposures would produce low but measurable systemic exposure in adults under typical use. (Sources: ECHA registration dossier; Tavares et al., PubMed).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- cyclamen aldehyde hamilelikte güvenli mi?
- ECHA registration data and many supplier/SDS classifications list cyclamen aldehyde as Repr. Cat. 2 / H361 (suspected of damaging fertility or the unborn child) based on repeat-dose and reproductive findings in rats reported in the REACH dossier; however the published mechanistic work shows the male reproductive toxicity is tied to a species‑specific CoA‑conjugate metabolic pathway in rats. Topical cosmetic exposures would produce low but measurable systemic exposure in adults under typical use. (Sources: ECHA registration dossier; Tavares et al., PubMed).
- cyclamen aldehyde emzirirken güvenli mi?
- Given the Repr. Cat.2/H361 classification reported in dossiers and the demonstrated metabolic mechanism causing male rat reproductive effects, the conservative hazard score is 2 (suspected). There are no human lactation/breastmilk transfer data; systemic exposure from topical use is expected to be low but measurable, so breastfeeding exposure is possible though not quantified (see ECHA dossier and animal/mechanistic study).
- cyclamen aldehyde bebek cildi için güvenli mi?
- Hazard and mechanism scores are driven by the same animal/mechanistic evidence (suspected reproductive toxicant with a demonstrated rat metabolic pathway). Exposure score is increased by +1 for baby skin (per your rubric) because topical use on infants gives higher per‑kg absorption and immature barrier — while direct infant-specific toxicology is lacking, absorption is plausibly higher than adults. No infant developmental or dermal‑transfer studies were located.
- VeriMom cyclamen aldehyde nasıl puanlıyor?
- VeriMom cyclamen aldehyde'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 20/100 (yüksek risk) olarak puanlar.
- Hamilelikte cyclamen aldehyde yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.