VeriMomHamilelikte chlorophene kullanmaktan kaçınmalı mıyım? | VeriMom
Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)
ECHA regulatory hazard statements
- •H351
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- chlorophene hamilelikte güvenli mi?
- Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)
- chlorophene emzirirken güvenli mi?
- Harmonised H361 (and related regulatory assessments) indicate suspected effects on fertility/development (h=2). Mechanistic and toxicology data from animal studies and in vitro mutagenicity support a demonstrated concern (m=2). For topical use, maternal systemic exposure is expected to be low but measurable (e=1); no reliable data were found documenting transfer into breastmilk, so exposure via breastmilk cannot be ruled out. Sources: ECHA CLP listing; NTP and other toxicology literature.
- chlorophene bebek cildi için güvenli mi?
- Hazard is the same (h=2) because of the harmonised H361f and supporting animal/toxicology data. Mechanistic evidence from studies (mutagenicity/in vivo toxicity) supports m=2. Exposure score is increased by +1 for baby skin (adult e=1 → baby e=2) because chlorophene is a relatively lipophilic, absorbable phenolic antimicrobial (logP ≈4.3) and infants (0–3 yrs) have higher surface‑area‑to‑weight and an immature barrier, increasing per‑kg systemic exposure from topical application. No infant‑specific toxicokinetic or dermal absorption studies were identified. Sources: ECHA CLP; NTP/toxicology studies; product/physicochemical records.
- VeriMom chlorophene nasıl puanlıyor?
- VeriMom chlorophene'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 20/100 (yüksek risk) olarak puanlar.
- Hamilelikte chlorophene yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.