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HIGH RISK

Hamilelikte captan kullanmaktan kaçınmalı mıyım? | VeriMom

Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.

ECHA regulatory hazard statements

  • H351
  • H361F

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

captan hamilelikte güvenli mi?
Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.
captan emzirirken güvenli mi?
Hazard and mechanism same rationale as for pregnancy (animal reproductive effects and mechanistic evidence). Dermal absorption from topical application is low (human toxicokinetic data and EPA/NPIC assessments), and while captan metabolites have been detected in animal milk in some studies, human milk transfer data are sparse — exposure via maternal topical use is therefore low but measurable. Sources: NPIC/EPA summaries, human dermal toxicokinetic study, animal milk data.
captan bebek cildi için güvenli mi?
Hazard (H361-level/suspected reproductive/developmental effects) and mechanistic findings apply (animal reproductive/ovarian effects, demonstrated oocyte toxicity). Dermal absorption for adults is low but measurable; per your scoring rules, infant skin exposure is increased by +1 because infant skin has higher permeability and higher surface-area-to-weight, so exposure for a baby (0–3 yr) is moderate. There is no infant-specific evidence to raise hazard or mechanism scores beyond the adult evidence. Sources: human dermal/tokinetic studies, EPA/NPIC, PubMed reproductive/toxicology studies.
VeriMom captan nasıl puanlıyor?
VeriMom captan'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 20/100 (yüksek risk) olarak puanlar.
Hamilelikte captan yerine neler kullanılabilir?
Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.

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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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