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Hamilelikte basic yellow 57 kullanmaktan kaçınmalı mıyım? | VeriMom

Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).

ECHA regulatory hazard statements

  • H361D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

basic yellow 57 hamilelikte güvenli mi?
Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).
basic yellow 57 emzirirken güvenli mi?
No human lactation studies were located. Animal developmental/reprotoxic findings indicate a suspected hazard (h=2). There is no evidence of a specific reproductive mechanism or documented transfer into milk; dermal systemic absorption from cosmetic use is low but measurable so maternal systemic exposure (and therefore potential, but likely low, transfer into breastmilk) is possible. (CIR; ECHA).
basic yellow 57 bebek cildi için güvenli mi?
Hazard score follows the animal developmental data (h=2). Mechanistic data for developmental/ endocrine modes of action were not identified (m=0). Measurable dermal bioavailability in in vitro skin studies (2–4% over 48 h) means exposure on infant skin is higher relative to adults due to immature barrier and higher surface‑area‑to‑weight; per scoring rules increase exposure by +1 giving e=2 for 0–3 y infants. No infant‑specific absorption studies were found. (CIR dermal absorption data; SCCS/CIR use‑levels).
VeriMom basic yellow 57 nasıl puanlıyor?
VeriMom basic yellow 57'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 33/100 (yüksek risk) olarak puanlar.
Hamilelikte basic yellow 57 yerine neler kullanılabilir?
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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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