VeriMomHamilelikte acrolein kullanmaktan kaçınmalı mıyım? | VeriMom
Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
ECHA regulatory hazard statements
- •H225
- •H330
- •H311
- •H300
- •H314
- •H400
- •H410
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- acrolein hamilelikte güvenli mi?
- Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
- acrolein emzirirken güvenli mi?
- Same hazard and mechanism considerations apply for lactation: animal reproductive/developmental effects and mechanistic evidence indicate a suspected reproductive hazard. For cosmetic topical use systemic absorption is expected to be low but measurable, so transfer into breastmilk could theoretically occur if significant systemic levels were reached, but typical cosmetic exposures are low.
- acrolein bebek cildi için güvenli mi?
- Hazard and mechanism same as for adults (suspected reproductive/developmental hazard with demonstrated mitochondrial/oocyte effects). Exposure score is increased by +1 for infants (per your rule) because acrolein has measurable dermal effects (it is skin‑corrosive/irritant and a small reactive molecule) so infants’ higher surface‑area‑to‑weight and immature barrier raise likely systemic uptake from topical application above adult levels.
- VeriMom acrolein nasıl puanlıyor?
- VeriMom acrolein'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 20/100 (yüksek risk) olarak puanlar.
- Hamilelikte acrolein yerine neler kullanılabilir?
- Benzer işlevli ve bilinen riski olmayan alternatifleri içeren listemize bakın.
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Tıbbi Sorumluluk Reddi
Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.