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Hamilelikte 5-bromo-5-nitro-1,3-dioxane kullanmaktan kaçınmalı mıyım? | VeriMom

Authoritative cosmetic reviews (CIR references) and regulatory reviews do not report convincing reproductive or teratogenic effects for 5-bromo-5-nitro-1,3-dioxane (bronidox); some sources report negative Ames tests and no clear repro/mutagenicity in the limited data available. Although some C&L notifications list H361 (suspected of damaging fertility or the unborn child), I could not find a harmonised Annex VI (legal) classification for this CAS — notifications/self-classifications alone do not raise the hazard score under your rules. Exposure from intended cosmetic topical use is low (used as a cosmetic preservative at up to ~0.1%, mainly in rinse-off products), so I scored exposure as 1 (low but measurable). Sources: CIR/regulatory reviews and ECHA registration/brief profile and reports cited below.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

5-bromo-5-nitro-1,3-dioxane hamilelikte güvenli mi?
Authoritative cosmetic reviews (CIR references) and regulatory reviews do not report convincing reproductive or teratogenic effects for 5-bromo-5-nitro-1,3-dioxane (bronidox); some sources report negative Ames tests and no clear repro/mutagenicity in the limited data available. Although some C&L notifications list H361 (suspected of damaging fertility or the unborn child), I could not find a harmonised Annex VI (legal) classification for this CAS — notifications/self-classifications alone do not raise the hazard score under your rules. Exposure from intended cosmetic topical use is low (used as a cosmetic preservative at up to ~0.1%, mainly in rinse-off products), so I scored exposure as 1 (low but measurable). Sources: CIR/regulatory reviews and ECHA registration/brief profile and reports cited below.
5-bromo-5-nitro-1,3-dioxane emzirirken güvenli mi?
No specific data were found showing reproductive or lactation-specific toxicity or transfer into breast milk. Mechanistic or experimental evidence of breast‑milk transfer is absent in the reviewed sources; therefore hazard and mechanism are scored 0 and exposure is scored 1 (low but measurable) for typical cosmetic topical use. See sources below for preservative use, regulatory restrictions and toxicology summaries.
5-bromo-5-nitro-1,3-dioxane bebek cildi için güvenli mi?
There is no infant-specific reproductive or developmental toxicity evidence. However, because bronidox is a small preservative used topically (and is reported to be skin‑irritating / a sensitizer at higher concentrations) I increased exposure by +1 for infants (immature barrier and higher surface-area-to-weight); this gives e=2. There is no infant-specific data to justify increasing hazard (h) or mechanism (m). Also note regulatory guidance restricts use to rinse‑off products and maximum concentrations (see sources).
VeriMom 5-bromo-5-nitro-1,3-dioxane nasıl puanlıyor?
VeriMom 5-bromo-5-nitro-1,3-dioxane'yi EU CosIng, ECHA sınıflandırmaları ve PubMed çalışmalarına göre 33/100 (yüksek risk) olarak puanlar.
Hamilelikte 5-bromo-5-nitro-1,3-dioxane yerine neler kullanılabilir?
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Tıbbi Sorumluluk Reddi

Bu bilgiler yalnızca eğitim amaçlıdır ve tıbbi tavsiye niteliği taşımaz. Güvenlik puanları kamuya açık verilere dayanmaktadır ve tüm riskleri yansıtmayabilir. Hamilelik veya emzirme döneminde herhangi bir ürünü kullanmadan önce her zaman sağlık uzmanınıza danışın.

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