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Is quaternium-18 safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
quaternium-18
NO KNOWN RISKS
100
/100
0

Pregnancy-safe products containing quaternium-18

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Authoritative references used to score this ingredient.

Frequently asked questions

Is quaternium-18 safe during pregnancy?
The Cosmetic Ingredient Review (CIR) safety assessment (and its amended report) concludes Quaternium-18 and its clay reaction products are 'safe as cosmetic ingredients in the present practices of use and concentration,' report that these quaternary ammonium compounds are poorly absorbed through the skin, and note no reported information concerning teratology or reproductive effects. No harmonised CLP reproductive classifications (H360/H361) were identified. ([cir-safety.org](https://cir-safety.org/sites/default/files/Quaternium-18.pdf))
Is quaternium-18 safe while breastfeeding?
No data were found showing reproductive or lactation-related toxicity or transfer via milk. CIR found little or no systemic toxicity and poor dermal absorption, and no peer‑reviewed reports of effects in breastfeeding were identified in the reviewed databases. Absent evidence or harmonised classification, default hazard/mechanism are 0. ([cir-safety.org](https://cir-safety.org/sites/default/files/Quaternium-18.pdf))
Is quaternium-18 safe for baby skin?
CIR reports Quaternium-18 and related clay products are poorly absorbed through adult skin and safe as used; therefore hazard/mechanism remain 0. Because infant (0–3 yr) skin has a less mature barrier and higher surface-area-to-weight ratio, exposure score is increased by +1 (from negligible adult absorption to low but measurable for infants) in the absence of infant‑specific dermal absorption data. ([cir-safety.org](https://cir-safety.org/sites/default/files/Quaternium-18.pdf))
How does VeriMom score quaternium-18?
VeriMom scores quaternium-18 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to quaternium-18?
See our curated list of pregnancy-safe alternatives to quaternium-18 based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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