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Is propanediol safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
propanediol
NO KNOWN RISKS
93
/100
0

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Frequently asked questions

Is propanediol safe during pregnancy?
No harmonised CLP reproductive classification for 1,3‑propanediol (CAS 504‑63‑2) and no CIR/SCCS finding of reproductive hazard; animal and human reproductive/teratology data do not indicate teratogenicity. Dermal absorption is measurable for small, hydrophilic diols used as solvents, so low but measurable systemic exposure is expected from topical use (e=1). Sources: ECHA Annex VI (no harmonised classification), CIR/SCCS summaries, PubChem, PubMed reviews.
Is propanediol safe while breastfeeding?
No evidence of reproductive or lactation-specific toxicity for 1,3‑propanediol; no mechanistic data indicating placental/breastmilk transfer or endocrine activity. Topical use may give low systemic levels, so low but measurable exposure for a lactating person is possible (e=1). Sources: PubChem, PubMed, ECHA dossiers, CosIng.
Is propanediol safe for baby skin?
No infant‑specific hazard data indicating reproductive or developmental toxicity; no known reproductive mechanism. Because 1,3‑propanediol is a small, water‑soluble, dermally absorbable solvent, exposure via baby skin is expected to be higher than adult per guidance (+1), so assign e=2. Sources: PubChem, CosIng, EWG, general dermal absorption considerations.
How does VeriMom score propanediol?
VeriMom scores propanediol at 93/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to propanediol?
See our curated list of pregnancy-safe alternatives to propanediol based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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