Is polyglyceryl-3 diisostearate safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
polyglyceryl-3 diisostearate
NO KNOWN RISKS100
/100
0









Pregnancy-safe products containing polyglyceryl-3 diisostearate

Palmer's
Palmer's Cocoa Butter All-In-One Everywhere Mini Balm
100/100

Earth Rhythm
Earth Rhythm Jojoba Grapeseed & Pomegranate Lip Serum
100/100

Rhythm
Rhythm Liplights Cream Lip Gloss
100/100

Supergoop!
Supergoop! Shimmershade Illuminating Cream Eyeshadow Spf 30
100/100

MakeupbyMario
MakeupbyMario Soft Pop Blush Stick
100/100

Dr. Pawpaw
Dr. PAWPAW Dr. Pawpaw Shea Butter Balm
100/100

Organic Harvest
Organic Harvest Sunscreen – Spf 30
99/100

PuroBIO
PuroBIO Concealer Pencil
99/100

organic kitchen
Organic Kitchen Don't Touch My Face Hydrophilic Cleansing Balm
99/100

Uriage
Uriage Bébé Cold Cream
99/100
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Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is polyglyceryl-3 diisostearate safe during pregnancy?
- CIR group safety assessment of polyglyceryl fatty‑acid esters (includes polyglyceryl‑3 diisostearate) concluded these ingredients are safe for use in cosmetics as currently used; no harmonised CLP reproductive or developmental classification was found on ECHA (Annex VI) for this substance. No peer‑reviewed studies were identified showing reproductive or teratogenic effects. (CIR; ECHA substance page).
- Is polyglyceryl-3 diisostearate safe while breastfeeding?
- No data indicating breast‑milk transfer or lactation‑specific toxicity; CIR concluded safe for cosmetic use and ECHA contains registration information but no harmonised reproductive hazards. No human/animal breastfeeding studies located that indicate risk.
- Is polyglyceryl-3 diisostearate safe for baby skin?
- Hazard and mechanism: no evidence of developmental/reproductive hazard specific to infants. Exposure: adults — CIR and typical ingredient profiles indicate negligible systemic hazard from normal topical cosmetic use; however infant skin has higher permeability and surface‑area‑to‑weight so exposure scoring is increased by +1 for 0–3‑year skin despite lack of evidence of harm. No infant‑specific absorption or toxicity studies located.
- How does VeriMom score polyglyceryl-3 diisostearate?
- VeriMom scores polyglyceryl-3 diisostearate at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to polyglyceryl-3 diisostearate?
- See our curated list of pregnancy-safe alternatives to polyglyceryl-3 diisostearate based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.