Is glycine max seed extract safe during pregnancy?

Pregnancy-Safe Alternatives to glycine max seed extract | VeriMom

Related ingredients

See also

• Is glycine max seed extract safe for babies?
• What are pregnancy-safe alternatives to glycine max seed extract?

Frequently asked questions

Is glycine max seed extract safe during pregnancy?

Glycine max seed extract itself is a botanical extract listed in cosmetic ingredient databases (CosIng/Supplier pages) with no EU Annex II/III listing or harmonised CLP classification found. However the extract contains isoflavones (genistein/daidzein), which have demonstrated estrogenic/ endocrine activity and produced reproductive/developmental effects in animal studies after perinatal or high-dose exposure, so a class-based/constituent concern is warranted (h=1). Mechanistic data show demonstrated estrogenic activity in vitro/in vivo (m=2). Dermal/topical exposure is likely low but measurable (e=1). ([specialchem.com](https://www.specialchem.com/cosmetics/inci-ingredients/glycine-max-seed-extract?utm_source=openai))

Is glycine max seed extract safe while breastfeeding?

No regulatory ban or harmonised CMR classification for Glycine max seed extract was identified; however the presence of isoflavones that can act as phytoestrogens supports a constituent-based concern (h=1). Mechanistic evidence of estrogenic activity exists (m=2). Dermal absorption and transfer into breast milk from topical use are not well quantified, but topical absorption is plausibly low-to-measurable (e=1). No specific human lactation transfer studies for cosmetic topical use were located. ([specialchem.com](https://www.specialchem.com/cosmetics/inci-ingredients/glycine-max-seed-extract?utm_source=openai))

Is glycine max seed extract safe for baby skin?

Hazard and mechanistic scores remain based on isoflavone content (h=1, m=2); there is animal evidence that neonatal/perinatal exposure to isoflavones can alter reproductive development, but no infant-specific dermal toxicity data for cosmetic topical application of Glycine max seed extract. Because infant skin has higher absorption, exposure score is increased by +1 (adult e=1 → baby e=2). There is no EU Annex II/III listing or harmonised CLP H360/H361 found for the extract itself. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/39884525/?utm_source=openai))

How does VeriMom score glycine max seed extract?

VeriMom scores glycine max seed extract at 60/100 (medium risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.

What are pregnancy-safe alternatives to glycine max seed extract?

See our curated list of pregnancy-safe alternatives to glycine max seed extract based on similar function and a no-known-risks safety band.