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Is dipotassium glycyrrhizate safe during pregnancy?

The Cosmetic Ingredient Review (CIR) safety assessment (peer‑reviewed) concluded these glycyrrhizate salts (including dipotassium glycyrrhizate) are expected to be poorly absorbed through skin and are not reproductive/developmental hazards in the cosmetic context; no harmonised CLP reproductive classifications were found on ECHA. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/17613133/))

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
dipotassium glycyrrhizate
NO KNOWN RISKS
100
/100
0

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Frequently asked questions

Is dipotassium glycyrrhizate safe during pregnancy?
The Cosmetic Ingredient Review (CIR) safety assessment (peer‑reviewed) concluded these glycyrrhizate salts (including dipotassium glycyrrhizate) are expected to be poorly absorbed through skin and are not reproductive/developmental hazards in the cosmetic context; no harmonised CLP reproductive classifications were found on ECHA. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/17613133/))
Is dipotassium glycyrrhizate safe while breastfeeding?
Topical cosmetic use is expected to produce negligible systemic exposure (CIR conclusion), so breastfeeding exposure via breastmilk is unlikely from normal topical use; no specific reproductive/ lactation hazards or harmonised classifications were identified. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/17613133/))
Is dipotassium glycyrrhizate safe for baby skin?
No evidence of reproductive or developmental hazard specific to infants; CIR notes poor dermal absorption for these salts, so hazard remains low. Per scoring rules, increase exposure (e) by +1 for 0–3‑yr skin because infant barrier is immature (adult e=0 → baby e=1). No infant‑specific data indicating higher hazard or mechanism were found. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/17613133/))
How does VeriMom score dipotassium glycyrrhizate?
VeriMom scores dipotassium glycyrrhizate at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to dipotassium glycyrrhizate?
See our curated list of pregnancy-safe alternatives to dipotassium glycyrrhizate based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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