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Is aminopropyl triethoxysilane safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
aminopropyl triethoxysilane
NO KNOWN RISKS
93
/100
0

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Frequently asked questions

Is aminopropyl triethoxysilane safe during pregnancy?
No harmonised CLP reproductive classification found for 3‑aminopropyltriethoxysilane (CAS 919‑30‑2) and available regulatory dossiers (ECHA/REACH registration and OECD SIDS) report prenatal/developmental studies with an identified NOAEL (oral OECD 414) but do not lead to harmonised H360/H361 classification. There are no SCCS or CIR cosmetic safety opinions restricting use in pregnancy. For topical cosmetic use systemic exposure is expected to be low but measurable, so exposure score =1. (See ECHA substance page; OECD SIDS/registration dossier).
Is aminopropyl triethoxysilane safe while breastfeeding?
No evidence of human developmental or reproductive effects relevant to lactation; no mechanism of transfer or endocrine activity reported in peer‑reviewed literature. By analogy with pregnancy, topical cosmetic use gives low but potentially measurable systemic exposure, so exposure score =1. (Sources: ECHA/registration summary; OECD SIDS).
Is aminopropyl triethoxysilane safe for baby skin?
No infant‑specific toxicity data were identified. Because baby skin (0–3 y) has a higher surface‑area‑to‑weight ratio and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → baby e=2). No studies report developmental effects specific to dermal exposure in infants. Regulatory dossiers report oral NOAELs but no dermal developmental hazard classification. (Sources: OECD SIDS; ECHA registration/summary; EWG entry).
How does VeriMom score aminopropyl triethoxysilane?
VeriMom scores aminopropyl triethoxysilane at 93/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to aminopropyl triethoxysilane?
See our curated list of pregnancy-safe alternatives to aminopropyl triethoxysilane based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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