vitex agnus castus extract é seguro durante a gravidez?

Alternativas seguras ao vitex agnus castus extract na gravidez | VeriMom

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vitex agnus castus extract é seguro durante a gravidez?

Multiple regulatory reviews and clinical reviews recommend avoiding Vitex agnus‑castus during pregnancy because the botanical has demonstrated effects on reproductive hormones (prolactin/progestogenic activity) and at least one animal study reported adverse pregnancy outcomes, so it is classed as 'suspected' reproductive hazard rather than confirmed harmonised CMR. (see TGA/EMA guidance; systematic review and PubMed animal study). Sources: TGA safety notice; systematic review/DARE; rat study. https://www.tga.gov.au/safety/safety-monitoring-and-information/safety-alerts/vitex-agnus-castus, https://www.ncbi.nlm.nih.gov/books/NBK71283/, https://pubmed.ncbi.nlm.nih.gov/35837144/

vitex agnus castus extract é seguro durante a amamentação?

Authoritative breastfeeding resources and reviews (LactMed / safety reviews) advise avoiding Vitex in lactation because it alters prolactin and may affect milk production and infant hormone exposure; this demonstrates a mechanistic concern (endocrine activity) and justifies a 'suspected' hazard score. Dermal/topical cosmetic use gives low systemic exposure but transfer into breastmilk is plausible with systemic administration; topical exposure is likely lower. Sources: LactMed (Chasteberry), systematic reviews, regulatory advisories. https://www.ncbi.nlm.nih.gov/books/NBK501807/, https://www.ncbi.nlm.nih.gov/books/NBK71283/

vitex agnus castus extract é seguro para a pele do bebê?

No direct evidence shows teratogenicity or infant‑skin specific reproductive toxicity from topical Vitex extracts, but the ingredient contains hormone‑active constituents (flavonoids, diterpenoids) which create a theoretical/class‑based concern for infants (hence h=1, m=1). Because infant skin has higher permeability, exposure score is increased by +1 relative to adult topical use (adult e=1 → infant e=2). Sources: phytochemistry summaries and reviews; translational guidance on avoiding systemic hormone modulators for infants. https://en.wikipedia.org/wiki/Vitex_agnus-castus, https://phcogrev.com/article/2018/12/23/104103phrevphrev2217

Como o VeriMom pontua vitex agnus castus extract?

O VeriMom pontua vitex agnus castus extract em 40/100 (risco médio) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.

Quais são as alternativas seguras a vitex agnus castus extract na gravidez?

Veja nossa lista curada de alternativas seguras a vitex agnus castus extract com base em função semelhante e classificação sem riscos conhecidos.