trichosanthes kirilowii root extract é seguro durante a gravidez?

Alternativas seguras ao trichosanthes kirilowii root extract na gravidez | VeriMom

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trichosanthes kirilowii root extract é seguro durante a gravidez?

Animal and mechanistic data show trichosanthin (from T. kirilowii root) is embryotoxic/abortifacient and has been used clinically to induce abortion, so reproductive hazard is supported (h=2). The mechanism is demonstrated (ribosome‑inactivating protein with demonstrated abortion mechanisms in experimental studies), so m=2. For topical cosmetic use exposure is likely low but measurable (e=1) because extracts are applied topically and some dermal uptake or local activity is possible depending on formulation; however systemic exposure from typical cosmetic topical use is likely limited. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

trichosanthes kirilowii root extract é seguro durante a amamentação?

Because the same demonstrable reproductive/embryotoxic hazard exists for trichosanthin and systemic exposure (even small) could theoretically transfer into breastmilk, breastfeeding is flagged at the same hazard and mechanism level (h=2, m=2). Expected dermal/topical exposure is low but measurable (e=1); no direct data on lactational transfer from topical cosmetic use were found. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

trichosanthes kirilowii root extract é seguro para a pele do bebê?

Hazard and mechanism are unchanged for infant skin (h=2, m=2) because the same toxic constituent (trichosanthin) is responsible. Exposure score is increased by +1 for baby skin to e=2 because infant skin has a higher surface‑area‑to‑weight ratio and less mature barrier, making dermal absorption and systemic exposure more likely from topical application of products containing the extract. No infant‑specific safety studies for topical T. kirilowii root extract were located. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

Como o VeriMom pontua trichosanthes kirilowii root extract?

O VeriMom pontua trichosanthes kirilowii root extract em 40/100 (risco médio) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.

Quais são as alternativas seguras a trichosanthes kirilowii root extract na gravidez?

Veja nossa lista curada de alternativas seguras a trichosanthes kirilowii root extract com base em função semelhante e classificação sem riscos conhecidos.