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retinoic acid é seguro durante a gravidez?

All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).

Ingredientes
retinoic acid
RISCO ALTO
13
/100
0

Alternativas seguras ao retinoic acid na gravidez | VeriMom

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Frequently asked questions

retinoic acid é seguro durante a gravidez?
All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
retinoic acid é seguro durante a amamentação?
Direct data on excretion of topical tretinoin into human milk are limited/ inconclusive, but the compound is systemically active and a retinoid; because of systemic teratogenicity and potential for transfer, caution is advised. Systemic absorption from topical use is generally low, so breast‑milk exposure is likely low but not well‑quantified in humans. (ECHA; FDA/label information; limited pharmacokinetic studies).
retinoic acid é seguro para a pele do bebê?
Tretinoin is a known teratogenic retinoid with well‑defined RAR/RXR activity. Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, so exposure score is increased by +1 relative to adults when topical absorption is measurable. Because tretinoin is prohibited in cosmetics in the EU and flagged as H360, it is not appropriate for use on infant skin. (ECHA; SCCS/CIR context; pediatric exposure considerations).
Como o VeriMom pontua retinoic acid?
O VeriMom pontua retinoic acid em 13/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
Quais são as alternativas seguras a retinoic acid na gravidez?
Veja nossa lista curada de alternativas seguras a retinoic acid com base em função semelhante e classificação sem riscos conhecidos.

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Aviso Médico

Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.

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