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poloxamine 504 é seguro durante a gravidez?

No authoritative reproductive hazard classification or safety assessment (SCCS/CIR/harmonised CLP) for Poloxamine 504 was identified, and published literature on poloxamines describes them as non‑reactive block copolymer surfactants used as excipients/carrier materials rather than reproductive toxicants. Searches of PubMed found formulation and delivery studies of poloxamines but no animal or human reproductive toxicity reports. Therefore default score is 0/0/0. (See PubMed discussion of poloxamines and supplier/cosmetic ingredient listings below).

Ingredientes
poloxamine 504
SEM RISCOS CONHECIDOS
100
/100
0

Related ingredients

Frequently asked questions

poloxamine 504 é seguro durante a gravidez?
No authoritative reproductive hazard classification or safety assessment (SCCS/CIR/harmonised CLP) for Poloxamine 504 was identified, and published literature on poloxamines describes them as non‑reactive block copolymer surfactants used as excipients/carrier materials rather than reproductive toxicants. Searches of PubMed found formulation and delivery studies of poloxamines but no animal or human reproductive toxicity reports. Therefore default score is 0/0/0. (See PubMed discussion of poloxamines and supplier/cosmetic ingredient listings below).
poloxamine 504 é seguro durante a amamentação?
No evidence found that poloxamine family members (including products marketed as Poloxamine/Tetronic) cause reproductive or lactation-related toxicity or have specific milk-transfer data. No harmonised CLP (ECHA Annex VI) classification or SCCS/CIR opinion indicating developmental or lactation hazards was found. In absence of positive data, default scores are 0/0/0. Sources include formulation and biocompatibility studies and supplier/cosmetic ingredient databases.
poloxamine 504 é seguro para a pele do bebê?
No infant‑specific reproductive or developmental hazard evidence was located. Mechanistic evidence for reproductive toxicity is absent, so h/m remain 0. Exposure (e) is increased by +1 for baby skin because poloxamines are surfactant/block copolymers with some potential for dermal uptake when used topically (and infant skin has higher absorption per weight); absorption is generally low but measurable in topical formulations described in the literature, so baby_skin e=1.
Como o VeriMom pontua poloxamine 504?
O VeriMom pontua poloxamine 504 em 100/100 (sem riscos conhecidos) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
Quais são as alternativas seguras a poloxamine 504 na gravidez?
Veja nossa lista curada de alternativas seguras a poloxamine 504 com base em função semelhante e classificação sem riscos conhecidos.

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Aviso Médico

Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.

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