VeriMomglycyrrhiza uralensis root extract é seguro durante a gravidez?
No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR conclusion that this extract is a reproductive teratogen; therefore hazard score remains 0 per rules. However, multiple peer-reviewed reports show constituent-specific endocrine activity in vitro (e.g., liquiritigenin is an ER agonist; glycyrrhizin/glycyrrhetinic acid have biological activity), so a demonstrated mechanistic effect is present (m=2). For topical use, systemic exposure is low but measurable depending on formulation, so exposure scored as 1. Sources: ECHA (no harmonised classification), PubMed (in vitro endocrine activity of licorice constituents), PubChem (constituent data), CosIng/EWG summaries.
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Frequently asked questions
- glycyrrhiza uralensis root extract é seguro durante a gravidez?
- No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR conclusion that this extract is a reproductive teratogen; therefore hazard score remains 0 per rules. However, multiple peer-reviewed reports show constituent-specific endocrine activity in vitro (e.g., liquiritigenin is an ER agonist; glycyrrhizin/glycyrrhetinic acid have biological activity), so a demonstrated mechanistic effect is present (m=2). For topical use, systemic exposure is low but measurable depending on formulation, so exposure scored as 1. Sources: ECHA (no harmonised classification), PubMed (in vitro endocrine activity of licorice constituents), PubChem (constituent data), CosIng/EWG summaries.
- glycyrrhiza uralensis root extract é seguro durante a amamentação?
- No human/animal data establishing reproductive or developmental toxicity via dermal cosmetic use or lactation and no harmonised classification; hazard remains 0. Mechanistic in vitro endocrine activity of constituents supports m=2. Dermal absorption from cosmetics is low but measurable; breastmilk transfer after topical cosmetic use is unlikely but not well studied, so exposure scored 1. Sources: PubMed (constituent endocrine activity), ECHA (no CLP reprotox classification), PubChem, EWG.
- glycyrrhiza uralensis root extract é seguro para a pele do bebê?
- No infant-specific evidence of reproductive/developmental toxicity from cosmetic topical use and no harmonised reprotoxic classification; hazard remains 0. Mechanistic evidence (in vitro estrogenic activity of constituents) justifies m=2. Exposure is increased for babies vs adults due to immature barrier and higher surface-area-to-weight; adult exposure scored 1 -> baby exposure increased to 2. Sources: PubMed (mechanistic studies on liquiritigenin/glycyrrhizin), CosIng/PubChem summaries, EWG.
- Como o VeriMom pontua glycyrrhiza uralensis root extract?
- O VeriMom pontua glycyrrhiza uralensis root extract em 80/100 (risco baixo) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a glycyrrhiza uralensis root extract na gravidez?
- Veja nossa lista curada de alternativas seguras a glycyrrhiza uralensis root extract com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.