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fisetin é seguro durante a gravidez?

No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).

Ingredientes
fisetin
SEM RISCOS CONHECIDOS
93
/100
0

Pregnancy-safe products containing fisetin

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Frequently asked questions

fisetin é seguro durante a gravidez?
No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).
fisetin é seguro durante a amamentação?
No authoritative safety assessment (CIR or SCCS) or harmonised classification indicating harm to breastfed children was found. No controlled human data showing transfer into milk or adverse effects in suckling offspring; some animal pregnancy studies showed protective effects rather than toxicity. Dermal exposure from cosmetics would be expected to give low but measurable systemic exposure in adults, so a low exposure score is used. Self‑classified SDS statements claiming reproductive/breastfeeding hazard are present for some supplier documents but are not equivalent to harmonised CLH and were not used to increase the hazard score.
fisetin é seguro para a pele do bebê?
No infant‑specific hazard evidence was identified. Per the scoring rules, because fisetin shows measurable dermal absorption in principle (small flavonol) the exposure score for baby skin is increased by +1 relative to adults to account for immature barrier and higher surface‑area‑to‑weight; there is no direct data showing increased hazard or infant‑specific mechanism, so hazard and mechanism scores remain at default.
Como o VeriMom pontua fisetin?
O VeriMom pontua fisetin em 93/100 (sem riscos conhecidos) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
Quais são as alternativas seguras a fisetin na gravidez?
Veja nossa lista curada de alternativas seguras a fisetin com base em função semelhante e classificação sem riscos conhecidos.

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Aviso Médico

Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.

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