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cis-3,5,5-trimethylcyclohexanol é seguro durante a gravidez?

No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found for cis-3,3,5‑trimethylcyclohexanol (CAS 933‑48‑2). PubMed/PMC pharmacokinetic/metabolism studies show the substance is absorbed/metabolised (glucuronidation in rat hepatocytes), indicating low but measurable systemic exposure after absorption, so exposure (e) is scored 1. Sources searched show hepatic/metabolism studies but no reproductive or teratogenic data. (See PubMed/PMC and ECHA registration data.)

Ingredientes
cis-3,5,5-trimethylcyclohexanol
SEM RISCOS CONHECIDOS
93
/100
0

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Frequently asked questions

cis-3,5,5-trimethylcyclohexanol é seguro durante a gravidez?
No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found for cis-3,3,5‑trimethylcyclohexanol (CAS 933‑48‑2). PubMed/PMC pharmacokinetic/metabolism studies show the substance is absorbed/metabolised (glucuronidation in rat hepatocytes), indicating low but measurable systemic exposure after absorption, so exposure (e) is scored 1. Sources searched show hepatic/metabolism studies but no reproductive or teratogenic data. (See PubMed/PMC and ECHA registration data.)
cis-3,5,5-trimethylcyclohexanol é seguro durante a amamentação?
No evidence of reproductive or lactation-specific toxicity or human teratogenicity was identified in the literature or in ECHA registration records. Metabolism data (rat hepatocytes; glucuronide formation) indicate the compound can be systemically available after absorption, so breastfeeding exposure is scored as low but measurable (e=1). No studies reporting transfer into milk or effects on nursing infants were found.
cis-3,5,5-trimethylcyclohexanol é seguro para a pele do bebê?
No infant-specific toxicity or developmental effects were identified. Because (a) the compound shows measurable uptake/metabolism in in vitro/in vivo models (rats/hepatocytes) and (b) infant skin has higher absorption per body weight, I increased exposure for baby skin by +1 (adult e=1 → baby e=2). There is no evidence to increase hazard (h) or mechanism (m) for infants in available studies.
Como o VeriMom pontua cis-3,5,5-trimethylcyclohexanol?
O VeriMom pontua cis-3,5,5-trimethylcyclohexanol em 93/100 (sem riscos conhecidos) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
Quais são as alternativas seguras a cis-3,5,5-trimethylcyclohexanol na gravidez?
Veja nossa lista curada de alternativas seguras a cis-3,5,5-trimethylcyclohexanol com base em função semelhante e classificação sem riscos conhecidos.

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Aviso Médico

Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.

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