allyl succinic anhydride é seguro durante a gravidez?
No harmonised CLP reproductive classifications, no SCCS/CIR safety assessment, and no peer‑reviewed reproductive or developmental toxicity data were found for allyl succinic anhydride (3‑allyl(dihydro)furan‑2,5‑dione, CAS 7539‑12‑0). Regulatory listings (ECHA PACT / substance pages) do not show a harmonised H360/H361 classification. Acute and irritation data indicate it is a skin/eye irritant and has measurable dermal toxicity (SDS reports dermal LD50 ≈320 mg/kg), so some dermal absorption is plausible with typical topical use — therefore exposure (e) is scored 1 for adults. (Sources: PubChem entry https://pubchem.ncbi.nlm.nih.gov/compound/111009; ECHA listing/PACT entries; manufacturer SDS https://www.gelest.com/wp-content/uploads/product_msds/ENEA0430-msds.pdf).
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Frequently asked questions
- allyl succinic anhydride é seguro durante a gravidez?
- No harmonised CLP reproductive classifications, no SCCS/CIR safety assessment, and no peer‑reviewed reproductive or developmental toxicity data were found for allyl succinic anhydride (3‑allyl(dihydro)furan‑2,5‑dione, CAS 7539‑12‑0). Regulatory listings (ECHA PACT / substance pages) do not show a harmonised H360/H361 classification. Acute and irritation data indicate it is a skin/eye irritant and has measurable dermal toxicity (SDS reports dermal LD50 ≈320 mg/kg), so some dermal absorption is plausible with typical topical use — therefore exposure (e) is scored 1 for adults. (Sources: PubChem entry https://pubchem.ncbi.nlm.nih.gov/compound/111009; ECHA listing/PACT entries; manufacturer SDS https://www.gelest.com/wp-content/uploads/product_msds/ENEA0430-msds.pdf).
- allyl succinic anhydride é seguro durante a amamentação?
- There is no evidence of reproductive or lactation-specific toxicity or breast‑milk transfer data in the literature or regulatory dossiers for this substance; no SCCS/CIR opinion was identified. Because the compound is an anhydride that can hydrolyse and manufacturer SDSs report dermal toxicity/irritation, low but measurable dermal absorption is possible, so adult exposure is scored 1. (Sources: PubChem https://pubchem.ncbi.nlm.nih.gov/compound/111009; Gelest SDS https://www.gelest.com/wp-content/uploads/product_msds/ENEA0430-msds.pdf; ECHA listings).
- allyl succinic anhydride é seguro para a pele do bebê?
- No infant-specific reproductive or toxicity data were identified. Per the scoring rules, because adult topical exposure is judged low but measurable (e=1) and available data show skin irritation/dermal toxicity (SDS), baby skin exposure is increased by +1 to e=2 due to immature barrier and higher surface‑area‑to‑weight; hazard and mechanism are unchanged in absence of infant‑specific evidence. (Sources: Gelest SDS https://www.gelest.com/wp-content/uploads/product_msds/ENEA0430-msds.pdf; PubChem https://pubchem.ncbi.nlm.nih.gov/compound/111009).
- Como o VeriMom pontua allyl succinic anhydride?
- O VeriMom pontua allyl succinic anhydride em 93/100 (sem riscos conhecidos) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a allyl succinic anhydride na gravidez?
- Veja nossa lista curada de alternativas seguras a allyl succinic anhydride com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.